ReviewJournal of endocrinological investigation2024
Psychological symptoms and brain activity alterations in women with PCOS and their relation to the reduced quality of life: a narrative review.
Review in Journal of endocrinological investigation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 31 citations in OpenAlex.
- Exploring the therapeutic impact of Salvia officinalis on lipid and oxidative stress markers in patients with polycystic ovary syndrome - a randomized placebo-controlled clinical trial.BMC complementary medicine and therapies · 2025Trial
- Non-clinical symptoms associated with polycystic ovary syndrome: evidence from a comparative study in Bangladesh.Journal of global health · 2026Article
- The causal relationship between polycystic ovary syndrome and structural changes in brain: a Mendelian randomization study.Brain imaging and behavior · 2026Article
- Article
- Impact of Soybean and Swimming Training Modifications on Inflammation, Neurogenesis and Cognitive Function in Polycystic Ovary Syndrome: Experimental and Bioinformatics Study.International journal of fertility & sterility · 2026Article
- Integrating evidence-based lifestyle and adjunct therapies for long-term management of polycystic ovary syndrome: mechanistic insights and clinical implications.Frontiers in reproductive health · 2026Review
- Challenges faced by women in the diagnosis and management of polycystic ovary syndrome: a qualitative study.Frontiers in medicine · 2026Article
- Health-related quality of life in women with normogonadotropic ovulatory dysfunction: a prospective cohort study.Frontiers in global women's health · 2026Article
- Causal Relationship Between 38 Dietary Factors, Including Sugar and Alcohol Intakes, and Polycystic Ovary Syndrome: A Two-Sample Mendelian Randomization Study.International journal of women's health · 2026Article
- From metabolic network to brain loop: unraveling the neuro-metabolic correlates in PCOS-related depression.Frontiers in endocrinology · 2026Article
- Rna analysis of the regulation of expression and alternative splicing in polycystic ovarian syndrome.RNA biology · 2025Article
- Why menstrual cycle irregularities belong in brain research.Nature medicine · 2025Article
- Review
- Association of vitamin D with depression and anxiety in polycystic ovary syndrome in Saudi Arabia.Journal of family medicine and primary care · 2025Article
- Sirtuins, redox, and metabolic pathways in the brain of female PCOS mice.Journal of assisted reproduction and genetics · 2025Article
- Article
- Comparative analysis of sexual function and psychological health in infertile patients with different ovarian dysfunctions.Sexual medicine · 2025Article
- Expression of transcription factors in polycystic ovary syndrome.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Article
- Ultrasound Assessment in Polycystic Ovary Syndrome Diagnosis: From Origins to Future Perspectives-A Comprehensive Review.Biomedicines · 2025Review
- Androgens and Hirsutism in a Large Cohort of Portuguese Women.Journal of clinical medicine · 2025Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPolycystic ovary syndrome (PCOS) is the most common feminine endocrine disorder, characterized by androgen excess, ovulatory dysfunction, and polycystic ovarian morphology. The negative impact of symptoms on the quality of life (QoL) of patients is still not clear. PURPOSE: The present review aimed at studying the impact of the symptoms, the psychological symptoms, and brain alterations in women with PCOS.
methodsA systematic search was undertaken for studies that assessed the impact of PCOS symptoms on QoL, psychological symptoms, and brain alterations in PCOS patients.
resultsMost of the information about QoL came from psychometric studies, which used culture-based questionnaires. Alterations of sleep quality, body image, and mood disorders can negatively affect the QoL of the patients. Sexual satisfaction and desire were affected by PCOS. Brain imaging studies showed functional alterations that are associated with impairments of visuospatial working memory, episodic and verbal memory, attention, and executive function.
conclusionsSeveral factors can negatively influence the quality of life of the patients, and they are directly related to hyperandrogenism and the risk of infertility. In particular, obesity, hirsutism, acne, and the fear of infertility can have a direct impact on self-esteem and sexual function. Metabolic and psychiatric comorbidities, such as mood, anxiety, and eating disorders, can affect the well-being of the patients. Moreover, specific cognitive alterations, such as impairments in attention and memory, can limit PCOS patients in a series of aspects of daily life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.