Evidence map›Paper›PMID 38485509›Full record

ArticleZoological research2024

RNA m6A dynamic modification mediated by nucleus-localized FTO is involved in follicular reserve.

Jiao-Na Zhang, Rui-Ting Wang, Francesca-Gioia Klinger, Shun-Feng Cheng, Wei Shen, Xiao-Feng Sun

Open access · diamondAbstract read
In one paragraph

Article in Zoological research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Role of epigenetic regulation in diminished ovarian reserve.Journal of assisted reproduction and genetics · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jiao-Na ZhangCollege of Life Sciences, Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, Qingdao Agricultural University, Qingdao, Shandong 266109, China.
Rui-Ting WangCollege of Life Sciences, Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, Qingdao Agricultural University, Qingdao, Shandong 266109, China.
Francesca-Gioia KlingerDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, Rome 00133, Italy.
Shun-Feng ChengCollege of Life Sciences, Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, Qingdao Agricultural University, Qingdao, Shandong 266109, China.
Wei ShenCollege of Life Sciences, Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, Qingdao Agricultural University, Qingdao, Shandong 266109, China. E-mail: wshen@qau.edu.cn.
Xiao-Feng SunCollege of Life Sciences, Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, Qingdao Agricultural University, Qingdao, Shandong 266109, China. E-mail: xfsun@qau.edu.cn.
Qingdao Agricultural University · CNUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In eukaryotic organisms, the most common internal modification of messenger RNA (mRNA) is N6-methyladenosine (m6A). This modification can be dynamically and reversibly controlled by specific enzymes known as m6A writers and erasers. The fat-mass and obesity-associated protein (FTO) catalyzes RNA demethylation and plays a critical role in various physiological and pathological processes. Our research identified dynamic alterations in both m6A and FTO during the assembly of primordial follicles, with an inverse relationship observed for m6A levels and nuclear-localized FTO expression. Application of

Indexed as

Alternative SplicingRNAAdenineAnimalsBiomarkersRNA, Messenger6-methyladenineAdenineBiomarkersRNARNA, MessengerAlternative splicingFTOm6AOvaryPrimordial follicle assembly

Identifiers

PMID38485509
PMCPMC11017081
OpenAlexW4389328469

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.