Evidence map›Paper›PMID 38485473›Full record

Trial reportBMJ open2024

Do smoking abstinence periods among pregnant smokers improve birth weight? A secondary analysis of a randomised, controlled trial.

Ivan Berlin, Leontine Goldzahl, Florence Jusot, Noemi Berlin

Registry-linked trialAbstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02606227 (Financial Incentive for Smoking Cessation in Pregnancy), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02606227 naunknown statusnot on this map

Financial Incentive for Smoking Cessation in Pregnancy

TypeinterventionalSponsorAssistance Publique - Hôpitaux de ParisRan2016 to 2019Enrolled480ConditionsPregnancy, SmokingArmsFinancial incentive, No financial incentive
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ivan BerlinDépartement de Pharmacologie Médicale, Hôpitaux Universitaires Pitié Salpêtrière - Charles Foix, Paris, France ivan.berlin@aphp.fr.ORCID 0000-0002-5928-5616
Leontine GoldzahlIESEG School of Management, Université de Lille, Lille, France.
Florence JusotParis Dauphine University, Paris, France.
Noemi BerlinCNRS, EconomiX, Université Paris Nanterre, Nanterre, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMaternal smoking during pregnancy is associated with low birth weight (LBW). Reduction of cigarette consumption does not seem to improve birth weight but it is not known whether implementation of periods of smoking abstinence improves it. We assessed whether the number of 7-day periods of smoking abstinence during pregnancy may help reduce the number of newborns with LBW. DESIGN AND

settingSecondary analysis of a randomised, controlled, multicentre, smoking cessation trial among pregnant smokers.

participantsPregnant women were included at <18 weeks of gestational age and assessed at face-to-face, monthly visits. Data of 407 singleton live births were analysed. PRIMARY OUTCOME MEASURE: Newborns with low birth weight.

results40 and 367 newborns were born with and without LBW, respectively. Adjusted for all available confounders, 3 or more periods of at least 7 days' smoking abstinence during pregnancy was associated with reduced likelihood of LBW compared with no abstinence periods (OR = 0.124, 95% CI 0.03 to 0.53, p = 0.005). Reduction of smoking intensity by at least 50% was not associated with birth weight.

conclusionAiming for several periods of smoking abstinence among pregnant smokers unable to remain continuously abstinent from smoking may be a better strategy to improve birth weight than reducing cigarette consumption. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov NCT02606227.

Indexed as

SmokersSmokingBirth WeightFemaleHumansInfant, NewbornParturitionPregnancyPregnant Peoplematernal medicineperinatologypreventive medicinerisk factors

Identifiers

PMID38485473
PMCPMC10941110

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.