Evidence map›Paper›PMID 38485266›Full record

ArticleGenes & development2024

A serine metabolic enzyme is flexing its muscle to help repair skeletal muscle.

Benjámin R Baráth, Laszlo Nagy

Open access · diamondAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes & development, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Benjámin R BaráthDepartment of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen 4032, Hungary.
Laszlo NagyDepartment of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen 4032, Hungary; lnagy@jhmi.edu.
Johns Hopkins University · USUniversity of Debrecen · HU

Funding

DHA-derived resolvin production andsignaling in tissue repair macrophages in metabolic diseaseR01DK124782 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI NAGY, LASZLO, SPITE, MATTHEW R · 2020 to 2023
$2.3M
Nuclear receptor, PPARg in macrophage polarization, hyperinflammatory gene expression and lung injuryR01HL170426 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Laszlo Nagy · 2024 to 2026
$1.9M
NHLBI NIH HHS R01 HL170426NIDDK NIH HHS R01 DK124782
6 · The paper itself

Abstract

Metabolic reprogramming of stem cells is a targetable pathway to control regeneration. Activation of stem cells results in down-regulation of oxidative phosphorylation (OXPHOS) and fatty acid oxidation (FAO) and turns on glycolysis to provide fuel for proliferation and specific signaling events. How cell type-specific events are regulated is unknown. In this issue of

Indexed as

Muscle, SkeletalSatellite Cells, Skeletal MuscleGlycolysisOxidative PhosphorylationStem Cellsagingglutamineketoglutaratemuscle regenerationmuscle stem cells

Identifiers

PMID38485266
PMCPMC10982685
OpenAlexW4392794881

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.