Evidence map›Paper›PMID 38485192›Full record

ArticleRNA (New York, N.Y.)2024

A scalable and cost-efficient rRNA depletion approach to enrich RNAs for molecular biology investigations.

Amrita Singh, Amy Xue, Justin Tai, Faith Mbadugha, Prisca Obi, Romario Mascarenhas, Antariksh Tyagi, Adamo Siena, Y Grace Chen

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Amrita Singh *Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519, USA.
Amy Xue *Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519, USA.
Justin TaiDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519, USA.
Faith MbadughaDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519, USA.
Prisca ObiDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519, USA.
Romario MascarenhasDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519, USA.
Antariksh TyagiYale Center for Genome Analysis, Yale University School of Medicine, New Haven, Connecticut 06519, USA.
Adamo SienaDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519, USA.
Y Grace ChenDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519, USA ye.grace.chen@yale.edu.
Yale University · US

Funding

The Regulation of Circular RNA FunctionsR35GM142687 · NIGMS · YALE UNIVERSITY · PI CHEN, YE GRACE · 2021 to 2025
$2.2M
NIGMS NIH HHS R35 GM142687
6 · The paper itself

Abstract

Transcriptomics analyses play pivotal roles in understanding the complex regulatory networks that govern cellular processes. The abundance of rRNAs, which account for 80%-90% of total RNA in eukaryotes, limits the detection and investigation of other transcripts. While mRNAs and long noncoding RNAs have poly(A) tails that are often used for positive selection, investigations of poly(A)

Indexed as

RNA, RibosomalAnimalsHumansMiceRatsRibonuclease HRNA, MessengerRibonuclease HRNA, MessengerRNA, RibosomalcircRNAeukaryoticpoly(A)−rRNA depletion

Identifiers

PMID38485192
PMCPMC11098455
OpenAlexW4392799212

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.