Evidence map›Paper›PMID 38485191›Full record

ArticleJournal for immunotherapy of cancer2024

Key role of CD4+ T cells in determining CD8 function during CAR-T cell manufacture.

J Joseph Melenhorst, Beatriz C Oliveira

Open access · goldAbstract readComment
In one paragraph

Article in Journal for immunotherapy of cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Naïve CD4Nature communications · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Generation and GMP scale-up of human CAR-T cells using non-viralMolecular therapy. Methods & clinical development · 2025
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

  • Comment on
    CD82023
5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

J Joseph MelenhorstCell Therapy & ImmunoEngineering Program, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA melenhj@ccf.org.
Beatriz C OliveiraCell Therapy & ImmunoEngineering Program, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA.
California University of Pennsylvania · USCleveland Clinic Lerner College of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CD4-Positive T-LymphocytesReceptors, Chimeric AntigenCD8-Positive T-LymphocytesHumansReceptors, Antigen, T-CellReceptors, Antigen, T-CellReceptors, Chimeric AntigenBiomarkerChimeric antigen receptor - CARImmunotherapy

Identifiers

PMID38485191
PMCPMC10941164
OpenAlexW4392820517

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.