ArticleThe Journal of cell biology1985
Fast axonal transport of foreign synaptic vesicles in squid axoplasm.
Article in The Journal of cell biology, 1985. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 43 citations in OpenAlex.
- Direct trafficking pathways from the Golgi apparatus to the plasma membrane.Seminars in cell & developmental biology · 2020Review
- Expression of beta-amyloid induced age-dependent presynaptic and axonal changes in Drosophila.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Dynein light chain regulates axonal trafficking and synaptic levels of Bassoon.The Journal of cell biology · 2009Article
- Fast anterograde transport of herpes simplex virus: role for the amyloid precursor protein of alzheimer's disease.Aging cell · 2003Article
- A developmentally regulated kinesin-related motor protein from Dictyostelium discoideum.Molecular biology of the cell · 1998Article
- ATP-dependent directional movement of rat synaptic vesicles injected into the presynaptic terminal of squid giant synapse.Proceedings of the National Academy of Sciences of the United States of America · 1989Article
- The role of kinesin and other soluble factors in organelle movement along microtubules.The Journal of cell biology · 1988Article
- The synaptic vesicle and the cytoskeleton.The Biochemical journal · 1987Review
- Rabies virus infection of cultured rat sensory neurons.Journal of virology · 1987Article
- Cross-bridges mediate anterograde and retrograde vesicle transport along microtubules in squid axoplasm.The Journal of cell biology · 1985Article
- Relationships between the rapid axonal transport of newly synthesized proteins and membranous organelles.Molecular neurobiologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Translocation of intracellular organelles requires interaction with the cellular cytoskeleton, but the membrane and cytoskeletal proteins involved in movement are unknown. Here we show that highly purified synaptic vesicles from electric fish added to extruded squid axoplasm can show ATP-dependent movement. The movement is indistinguishable from that of endogenous vesicles and has a slight preference for the orthograde direction. In the presence of a nonhydrolyzable ATP analog, the synaptic vesicles bind to axoplasmic fibers but do not move. Elastase treatment of vesicles inhibits both binding and movement. We conclude that a protein component on the surface of cholinergic synaptic vesicles from electric fish is conserved during evolution and so can be recognized by the organelle-translocating machinery of the squid axon, resulting in ATP-dependent movement. Synaptic vesicles apparently retain the capacity for fast axonal transport, even after they reach their intracellular destination.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.