Evidence map›Paper›PMID 38484191›Full record

ArticleJCO global oncology2024

Artificial Intelligence-Based Radiotherapy Contouring and Planning to Improve Global Access to Cancer Care.

Laurence E Court, Ajay Aggarwal, Anuja Jhingran, Komeela Naidoo, Tucker Netherton, Adenike Olanrewaju, Christine Peterson, Jeannette Parkes, Hannah Simonds, Christoph Trauernicht and 3 more

Erratum issuedAbstract read
In one paragraph

Article in JCO global oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Laurence E CourtUniversity of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0002-3241-6145
Ajay AggarwalGuy's and St Thomas Hospitals, London, United Kingdom.ORCID 0000-0001-9645-6659
Anuja JhingranUniversity of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0002-0697-1815
Komeela NaidooStellenbosch University, Stellenbosch, South Africa.ORCID 0000-0003-2905-9973
Tucker NethertonUniversity of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0003-1583-7121
Adenike OlanrewajuUniversity of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0002-9012-8774
Christine PetersonUniversity of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0003-3316-0468
Jeannette ParkesUniversity of Cape Town, Cape Town, South Africa.ORCID 0000-0002-7735-1111
Hannah SimondsStellenbosch University, Stellenbosch, South Africa.ORCID 0000-0002-4442-6068
Christoph TrauernichtStellenbosch University, Stellenbosch, South Africa.ORCID 0000-0002-0259-2148
Lifei ZhangUniversity of Texas MD Anderson Cancer Center, Houston, TX.
Beth M BeadleStanford University, Stanford, CA.ORCID 0000-0001-5497-2831
Radiation Planning Assistant Consortium

Funding

NCI NIH HHSWellcome Trust
6 · The paper itself

Abstract

purposeIncreased automation has been identified as one approach to improving global cancer care. The Radiation Planning Assistant (RPA) is a web-based tool offering automated radiotherapy (RT) contouring and planning to low-resource clinics. In this study, the RPA workflow and clinical acceptability were assessed by physicians around the world.

methodsThe RPA output for 75 cases was reviewed by at least three physicians; 31 radiation oncologists at 16 institutions in six countries on five continents reviewed RPA contours and plans for clinical acceptability using a 5-point Likert scale.

resultsFor cervical cancer, RPA plans using bony landmarks were scored as usable as-is in 81% (with minor edits 93%); using soft tissue contours, plans were scored as usable as-is in 79% (with minor edits 96%). For postmastectomy breast cancer, RPA plans were scored as usable as-is in 44% (with minor edits 91%). For whole-brain treatment, RPA plans were scored as usable as-is in 67% (with minor edits 99%). For head/neck cancer, the normal tissue autocontours were acceptable as-is in 89% (with minor edits 97%). The clinical target volumes (CTVs) were acceptable as-is in 40% (with minor edits 93%). The volumetric-modulated arc therapy (VMAT) plans were acceptable as-is in 87% (with minor edits 96%). For cervical cancer, the normal tissue autocontours were acceptable as-is in 92% (with minor edits 99%). The CTVs for cervical cancer were scored as acceptable as-is in 83% (with minor edits 92%). The VMAT plans for cervical cancer were acceptable as-is in 99% (with minor edits 100%).

conclusionThe RPA, a web-based tool designed to improve access to high-quality RT in low-resource settings, has high rates of clinical acceptability by practicing clinicians around the world. It has significant potential for successful implementation in low-resource clinics.

Indexed as

Breast NeoplasmsUterine Cervical NeoplasmsArtificial IntelligenceFemaleHumansMastectomyRadiotherapy Planning, Computer-Assisted

Identifiers

PMID38484191
PMCPMC10954080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.