Evidence map›Paper›PMID 38484041›Full record

ArticlePLoS neglected tropical diseases2024

Successful introgression of wMel Wolbachia into Aedes aegypti populations in Fiji, Vanuatu and Kiribati.

Cameron P Simmons, Wesley Donald, Lekon Tagavi, Len Tarivonda, Timothy Quai, Raynelyn Tavoa, Tebikau Noran, Erirau Manikaoti, Lavinia Kareaua, Tabomoa Tinte Abwai and 40 more

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
7.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. LaboratoryFrontiers in cellular and infection microbiology · 2026
    Article
  5. Review
  6. Infections ofViruses · 2025
    Article
  7. Counting rareMicrobiology spectrum · 2025
    Article
  8. ExploitingPathogens (Basel, Switzerland) · 2025
    Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

50 authors at 4 institutions in 4 countries.

Cameron P SimmonsWorld Mosquito Program, Monash University, Clayton, Australia.ORCID 0000-0002-9039-7392
Wesley DonaldMinistry of Health, Government of Vanuatu, Port Vila, Vanuatu.
Lekon TagaviMinistry of Health, Government of Vanuatu, Port Vila, Vanuatu.
Len TarivondaMinistry of Health, Government of Vanuatu, Port Vila, Vanuatu.
Timothy QuaiWorld Mosquito Program, Port Vila, Vanuatu.
Raynelyn TavoaVanuatu Red Cross Society, Port Vila, Vanuatu.
Tebikau NoranMinistry of Health and Medical Services, Kiribati Government, Kiribati.
Erirau ManikaotiMinistry of Health and Medical Services, Kiribati Government, Kiribati.
Lavinia KareauaMinistry of Health and Medical Services, Kiribati Government, Kiribati.
Tabomoa Tinte AbwaiMinistry of Health and Medical Services, Kiribati Government, Kiribati.
Dip ChandMinistry of Health and Medical Services, Government of Fiji, Suva, Fiji.
Vineshwaran RamaMinistry of Health and Medical Services, Government of Fiji, Suva, Fiji.
Vimal DeoMinistry of Health and Medical Services, Government of Fiji, Suva, Fiji.
Kharishma Karti DeoMinistry of Health and Medical Services, Government of Fiji, Suva, Fiji.
Aminiasi TavuiiWorld Mosquito Program, Monash University, Clayton, Australia.
Wame ValentineWorld Mosquito Program, Suva, Fiji.
Raviikash PrasadWorld Mosquito Program, Suva, Fiji.
Eremasi SeruWorld Mosquito Program, Suva, Fiji.
Leikitah NaitukuWorld Mosquito Program, Suva, Fiji.
Anaseini RatuWorld Mosquito Program, Monash University, Clayton, Australia.
Mark HeskethWorld Mosquito Program, Monash University, Clayton, Australia.
Nichola KennyWorld Mosquito Program, Monash University, Clayton, Australia.
Sarah C BeebeWorld Mosquito Program, Monash University, Clayton, Australia.
Anjali A GoundarWorld Mosquito Program, Monash University, Clayton, Australia.
Andrew McCawWorld Mosquito Program, Monash University, Clayton, Australia.
Molly BuntineWorld Mosquito Program, Monash University, Clayton, Australia.
Ben GreenWorld Mosquito Program, Monash University, Clayton, Australia.
Tibor FrossardWorld Mosquito Program, Monash University, Clayton, Australia.
Jeremie R L GillesWorld Mosquito Program, Monash University, Clayton, Australia.
D Albert JoubertWorld Mosquito Program, Monash University, Clayton, Australia.
Geoff WilsonWorld Mosquito Program, Monash University, Clayton, Australia.
Le Quyen DuongWorld Mosquito Program, Monash University, Clayton, Australia.
Jean B BouvierWorld Mosquito Program, Monash University, Clayton, Australia.
Darren StanfordWorld Mosquito Program, Monash University, Clayton, Australia.
Carolyn ForderWorld Mosquito Program, Monash University, Clayton, Australia.
Johanna M DuyvestynWorld Mosquito Program, Monash University, Clayton, Australia.
Etiene C PacidônioWorld Mosquito Program, Monash University, Clayton, Australia.
Heather A FloresWorld Mosquito Program, Monash University, Clayton, Australia.
Natalie WittmeierWorld Mosquito Program, Monash University, Clayton, Australia.
Kate RetzkiWorld Mosquito Program, Monash University, Clayton, Australia.
Peter A RyanWorld Mosquito Program, Monash University, Clayton, Australia.
Jai A DentonWorld Mosquito Program, Monash University, Clayton, Australia.ORCID 0000-0002-5259-4221
Ruth SmithymanWorld Mosquito Program, Monash University, Clayton, Australia.
Stephanie K TanamasWorld Mosquito Program, Monash University, Clayton, Australia.
Peter KyrylosWorld Mosquito Program, Monash University, Clayton, Australia.
Yi DongWorld Mosquito Program, Monash University, Clayton, Australia.
Anam KhalidWorld Mosquito Program, Monash University, Clayton, Australia.
Lauren HodgsonWorld Mosquito Program, Monash University, Clayton, Australia.
Katherine L AndersWorld Mosquito Program, Monash University, Clayton, Australia.
Scott L O'NeillWorld Mosquito Program, Monash University, Clayton, Australia.
Monash University · AUVanuatu Cultural Centre · VUMinistry of Fisheries and Marine Resource Development · KIMinistry Of Health · FJ

Funding

Commonwealth of Australia
6 · The paper itself

Abstract

Pacific Island countries have experienced periodic dengue, chikungunya and Zika outbreaks for decades. The prevention and control of these mosquito-borne diseases rely heavily on control of Aedes aegypti mosquitoes, which in most settings are the primary vector. Introgression of the intracellular bacterium Wolbachia pipientis (wMel strain) into Ae. aegypti populations reduces their vector competence and consequently lowers dengue incidence in the human population. Here we describe successful area-wide deployments of wMel-infected Ae. aegypti in Suva, Lautoka, Nadi (Fiji), Port Vila (Vanuatu) and South Tarawa (Kiribati). With community support, weekly releases of wMel-infected Ae. aegypti mosquitoes for between 2 to 5 months resulted in wMel introgression in nearly all locations. Long term monitoring confirmed a high, self-sustaining prevalence of wMel infecting mosquitoes in almost all deployment areas. Measurement of public health outcomes were disrupted by the Covid19 pandemic but are expected to emerge in the coming years.

Indexed as

AedesDengueDengue VirusWolbachiaZika VirusZika Virus InfectionAnimalsFijiHumansMosquito VectorsVanuatu

Identifiers

PMID38484041
PMCPMC10980184
OpenAlexW4392796895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.