Evidence map›Paper›PMID 38483602›Full record

ArticleCardiovascular and interventional radiology2024

Percutaneous Image-Guided Cryoablation of Endophytic Renal Cell Carcinoma.

Christian Greve Jensen, Marco Dybdahl, John Valtersson, Bo Redder Mussmann, Louise Aarup Duus, Theresa Junker, Pia Iben Pietersen, Lars Lund, Brian T Welch, Ole Graumann

Open access · hybridAbstract read
In one paragraph

Article in Cardiovascular and interventional radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Christian Greve JensenFaculty of Health Sciences, Medicine, University of Southern Denmark (SDU), Odense, Denmark.
Marco DybdahlResearch and Innovation Unit of Radiology - UNIFY, SDU, Odense, Denmark.
John ValterssonResearch and Innovation Unit of Radiology - UNIFY, SDU, Odense, Denmark.
Bo Redder MussmannResearch and Innovation Unit of Radiology - UNIFY, SDU, Odense, Denmark.
Louise Aarup DuusResearch and Innovation Unit of Radiology - UNIFY, SDU, Odense, Denmark.
Theresa JunkerResearch and Innovation Unit of Radiology - UNIFY, SDU, Odense, Denmark.
Pia Iben PietersenResearch and Innovation Unit of Radiology - UNIFY, SDU, Odense, Denmark.
Lars LundDepartment of Urology, OUH, Odense, Denmark.
Brian T WelchDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Ole GraumannFaculty of Health Sciences, Medicine, University of Southern Denmark (SDU), Odense, Denmark. olegraumann@dadlnet.dk.ORCID http://orcid.org/0000-0002-9663-8361
Odense Municipality · DKOdense University Hospital · DKSyddansk Innovation (Denmark) · DKUniversity of Southern Denmark · DKMayo Clinic in Arizona · USOsloMet – Oslo Metropolitan University · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEndophytic renal cancer treatment is a challenge. Due to difficulties in endophytic tumor visualization during surgical extirpation, image-guided percutaneous cryoablation (PCA) is an attractive alternative. The minimally invasive nature of PCA makes it favorable for comorbid patients as well as patients in which surgery is contraindicated. Oncological outcomes and complications after PCA of endophytic biopsy-proven renal cell carcinoma (RCC) were reviewed in this study. MATERIALS AND

methodsPatients were included after a multidisciplinary team conference from January 2015 to November 2021. Inclusion criteria were endophytic biopsy-proven T1 RCC treated with PCA with one year of follow-up. Complications were reported according to the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) classification system and the Clavien-Dindo classification (CDC) system. Major complications were defined as a grade ≥ 3 according to the CDC.

resultsFifty-six patients were included with a total of 56 endophytic tumors treated during 61 PCA sessions. The median RENAL nephrometry score was 9 (IQR 2), and the mean tumor size was 25.7 mm (SD ± 8.9 mm). Mean hospitalization time was 0.39 (SD ± 1.1) days. At a mean follow-up of 996 days (SD ± 559), 86% of tumors were recurrence free after one PCA. No patients progressed to metastatic disease. According to the CIRSE classification, 10.7% (n = 6) had grade 3 complications, and 5.4% (n = 3) had CDC major complications.

conclusionThis study demonstrates that PCA of endophytic biopsy-proven T1 RCC is safe with few major complications and excellent local tumor control rates at almost three-year mean follow-up. LEVEL OF EVIDENCE 3: Retrospective cohort study.

Indexed as

Carcinoma, Renal CellCryosurgeryKidney NeoplasmsHumansKidneyRetrospective StudiesTreatment OutcomeAblationCryoablationEndophytic tumorPCAPercutaneousRCCRenal cancer

Identifiers

PMID38483602
PMCPMC10997531
OpenAlexW4392817838

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.