Evidence map›Paper›PMID 38483584›Full record

ReviewArchives of toxicology2024

Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nanomaterials with multiple enzyme-mimicking activities, and low-molecular-weight antioxidants.

Klaudia Jomova, Suliman Y Alomar, Saleh H Alwasel, Eugenie Nepovimova, Kamil Kuca, Marian Valko

Open access · hybridAbstract readReview
In one paragraph

Review in Archives of toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 583 papers.

0numbers the graph read from it
0cells of the map it votes in
583citing papers in PubMed
112.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

583 citing papers in PubMed, 958 citations in OpenAlex.

  1. Trial
  2. Significance of GSH and HRedox report : communications in free radical research · 2026
    Review
  3. The toxic footprint of lead exposure: oxido-inflammatory biomarkers in urban populations of Niger Delta, Nigeria.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Design rules for externally triggered drug uncaging under optical and radiolytic regimes.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
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  14. Article
  15. Article
  16. Review
  17. Review
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  19. Article
  20. Article

523 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Klaudia JomovaDepartment of Chemistry, Faculty of Natural Sciences, Constantine The Philosopher University in Nitra, Nitra, 949 74, Slovakia.
Suliman Y AlomarDoping Research Chair, Zoology Department, College of Science, King Saud University, 11451, Riyadh, Saudi Arabia.
Saleh H AlwaselZoology Department, College of Science, King Saud University, 11451, Riyadh, Saudi Arabia.
Eugenie NepovimovaDepartment of Chemistry, Faculty of Sciences, University of Hradec Kralove, 50005, Hradec Kralove, Czech Republic.
Kamil KucaDepartment of Chemistry, Faculty of Sciences, University of Hradec Kralove, 50005, Hradec Kralove, Czech Republic.
Marian ValkoFaculty of Chemical and Food Technology, Slovak University of Technology, 812 37, Bratislava, Slovakia. marian.valko@stuba.sk.ORCID 0000-0001-7483-0267
King Saud University · SAConstantine the Philosopher University in Nitra · SKSlovak University of Technology in Bratislava · SKUniversity Hospital Hradec Králové · CZUniversity of Hradec Králové · CZ

Funding

Agentúra Ministerstva Školstva, Vedy, Výskumu a Športu SR 1/0542/24Deanship of Scientific Research, King Saud University RSP2024R35Ministerstvo Zdravotnictví Ceské Republiky 00179906Ministerstvo Zdravotnictví Ceské Republiky UHHKUniverzita Hradec Králové Excelence PrF UHK 2208/2023-2024
6 · The paper itself

Abstract

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are well recognized for playing a dual role, since they can be either deleterious or beneficial to biological systems. An imbalance between ROS production and elimination is termed oxidative stress, a critical factor and common denominator of many chronic diseases such as cancer, cardiovascular diseases, metabolic diseases, neurological disorders (Alzheimer's and Parkinson's diseases), and other disorders. To counteract the harmful effects of ROS, organisms have evolved a complex, three-line antioxidant defense system. The first-line defense mechanism is the most efficient and involves antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx). This line of defense plays an irreplaceable role in the dismutation of superoxide radicals (O

Indexed as

AntioxidantsNeoplasmsAnthocyaninsChronic DiseaseHumansHydrogen PeroxideNitric OxideOxidative StressPeroxynitrous AcidReactive Oxygen SpeciesSuperoxide DismutaseSuperoxidesAnthocyaninsAntioxidantsHydrogen PeroxideNitric OxidePeroxynitrous AcidReactive Oxygen SpeciesSuperoxide DismutaseSuperoxidesAntioxidant enzymesChronic diseaseEnzyme mimicsLow-molecular antioxidantsOxidative stressROS

Identifiers

PMID38483584
PMCPMC11303474
OpenAlexW4392817459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.