Evidence map›Paper›PMID 38483448›Full record

ArticleeLife2024

A common

Jaaved Mohammed, Neha Arora, Harold S Matthews, Karissa Hansen, Maram Bader, Susan Walsh, John R Shaffer, Seth M Weinberg, Tomek Swigut, Peter Claes and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. A commoneLife · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Jaaved MohammedDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, United States.ORCID https://orcid.org/0000-0002-7053-5575
Neha AroraDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, United States.
Harold S MatthewsDepartment of Human Genetics, KU Leuven, Leuven, Belgium.
Karissa HansenProgram in Craniofacial Biology, Department of Orofacial Sciences and Department of Anatomy, Institute of Human Genetics, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, United States.
Maram BaderDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, United States.
Susan WalshDepartment of Biology, Indiana University Indianapolis, Indianapolis, United States.
John R ShafferCenter for Craniofacial and Dental Genetics, Department of Oral and Craniofacial Sciences, University of Pittsburgh, Pittsburgh, United States.ORCID https://orcid.org/0000-0003-1897-1131
Seth M WeinbergCenter for Craniofacial and Dental Genetics, Department of Oral and Craniofacial Sciences, University of Pittsburgh, Pittsburgh, United States.
Tomek SwigutDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, United States.ORCID https://orcid.org/0000-0002-7649-6781
Peter ClaesDepartment of Human Genetics, KU Leuven, Leuven, Belgium.
Licia SelleriProgram in Craniofacial Biology, Department of Orofacial Sciences and Department of Anatomy, Institute of Human Genetics, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, United States.
Joanna WysockaDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, United States.ORCID https://orcid.org/0000-0002-6909-6544
Stanford University · USUniversity of California, San Francisco · USUniversity of Pittsburgh · USHoward Hughes Medical Institute · USIndiana University Indianapolis · USKU Leuven · BEMurdoch Children's Research Institute · AU

Funding

PREDOCTORAL TRAINING IN DEVELOPMENTAL BIOLOGYT32HD007470 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Todd Nystul · 1994 to 2026
$7.7M
The Genetic Architecture of Human Facial MorphologyR01DE027023 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CLAES, PETER, SHAFFER, JOHN R · 2017 to 2024
$5.2M
NICHD NIH HHS T32 HD007470NIDCR NIH HHS DE027023NIDCR NIH HHS R01 DE027023
6 · The paper itself

Abstract

Genome-wide association studies (GWAS) identified thousands of genetic variants linked to phenotypic traits and disease risk. However, mechanistic understanding of how GWAS variants influence complex morphological traits and can, in certain cases, simultaneously confer normal-range phenotypic variation and disease predisposition, is still largely lacking. Here, we focus on

Indexed as

ChondrogenesisGenome-Wide Association StudyAnimalsCell Cycle ProteinsFaceHeadHumansMiceNuclear ProteinsProtein-Tyrosine KinasesSkullCell Cycle ProteinsMad1l1 protein, mouseNuclear ProteinsPKDCC protein, humanProtein-Tyrosine Kinasescraniofacial developmentdevelopmental biologyenhancer evolutionevolutionary biologyface-shape variationGWAShumanmouse

Identifiers

PMID38483448
PMCPMC10939500
OpenAlexW4392801146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.