Evidence map›Paper›PMID 38483314›Full record

ArticleeLife2024

Deciphering the genetic interactions between Pou4f3, Gfi1, and Rbm24 in maintaining mouse cochlear hair cell survival.

Guangqin Wang, Yunpeng Gu, Zhiyong Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 3 countries.

Guangqin WangInstitute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.ORCID https://orcid.org/0000-0002-8613-7619
Yunpeng GuInstitute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.
Zhiyong LiuInstitute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.ORCID https://orcid.org/0000-0002-9675-1233
Chinese Academy of Sciences · CN

Funding

Ministry of Science and Technology of the People's Republic of China 2021YFA1101804National Natural Science Foundation of China 32321163648
6 · The paper itself

Abstract

Mammals harbor a limited number of sound-receptor hair cells (HCs) that cannot be regenerated after damage. Thus, investigating the underlying molecular mechanisms that maintain HC survival is crucial for preventing hearing impairment. Intriguingly,

Indexed as

Genetic TherapyTranscription FactorsAnimalsAnimals, Genetically ModifiedDNA-Binding ProteinsHair Cells, AuditoryHomeodomain ProteinsMammalsMiceRNA-Binding ProteinsSoundTranscription Factor Brn-3CDNA-Binding ProteinsGfi1 protein, mouseHomeodomain ProteinsPou4f3 protein, mouseRbm24 protein, mouseRNA-Binding ProteinsTranscription Factor Brn-3CTranscription Factorscochleadevelopmental biologyGfi1hair cell deathhair cellsmouseneurosciencePou4f3Rbm24

Identifiers

PMID38483314
PMCPMC10939501
OpenAlexW4385252562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.