Observational studyRadiology. Cardiothoracic imaging2024
Impact of Smoking on Coronary Volume-to-Myocardial Mass Ratio: An ADVANCE Registry Substudy.
Open access · goldAbstract readObservational Study
In one paragraph
Observational study in Radiology. Cardiothoracic imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 7 citations in OpenAlex.
- Effect of smoking on the diagnostic performance of computational fluid dynamics-derived CT-derived fractional flow reserve: a cross-sectional study.Quantitative imaging in medicine and surgery · 2026Article
- Coronary CT angiography-derived epicardial coronary volume to left ventricular mass ratio associated with myocardial ischemic events in patients with type 2 diabetes mellitus.BMC cardiovascular disorders · 2026Article
- Coronary artery volume to left ventricular myocardial mass ratio in detecting primary microvascular angina: a retrospective observational study in Chinese population.BMC cardiovascular disorders · 2025Observational
- Review
- Computed tomography-based coronary lumen volume to myocardial mass ratio in patients undergoing transcatheter aortic valve replacement: a novel method for risk assessment.BMC cardiovascular disorders · 2025Article
- The impact of dilated cardiomyopathy in relation to coronary artery dimensions and left ventricle myocardial mass in a model with excluded coronary atherosclerosis.Cardiology journal · 2025Article
- Coronary Volume-to-Myocardial Mass Ratio Giving Additional Insights in Coronary Artery Disease Pathophysiology.Radiology. Cardiothoracic imaging · 2024Article
Corrections and comments
- Commented on by
Authors and funding
22 authors at 15 institutions in 7 countries.
Kenneth R HolmesFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).ORCID 0000-0002-4122-0355
Gaurav S GulsinFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).ORCID 0000-0002-1740-9270
Timothy A FairbairnFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).ORCID 0000-0003-1491-6231
Lynne Hurwitz-KoweekFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).ORCID 0000-0001-9990-3397
Hitoshi MatsuoFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).ORCID 0000-0002-1571-6533
Bjarne L NørgaardFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).ORCID 0000-0002-4758-7203
Jesper M JensenFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).
Niels-Peter Rønnow SandFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).
Koen NiemanFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).ORCID 0000-0002-8312-0598
Jeroen J BaxFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).ORCID 0000-0001-7368-0500
Gianluca PontoneFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).ORCID 0000-0002-1339-6679
Kavitha M ChinnaiyanFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).ORCID 0000-0002-1337-826X
Mark G RabbatFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).
Tetsuya AmanoFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).ORCID 0000-0002-6833-3675
Tomohiro KawasakiFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).ORCID 0000-0002-4795-7745
Takashi AkasakaFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).
Hironori KitabataFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).
Campbell RogersFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).ORCID 0000-0003-3955-7650
Manesh R PatelFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).ORCID 0000-0002-2393-0855
Geoffrey W PayneFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).ORCID 0000-0003-2809-9711
Jonathon A LeipsicFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).ORCID 0000-0002-6133-8334
Stephanie L SellersFrom the Department of Radiology (K.R.H., G.S.G., J.A.L., S.L.S.) and Centre for Heart Lung Innovation & Providence Research (G.S.G., J.A.L., S.L.S.), St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6; Liverpool Heart and Chest Hospital, Liverpool, England (T.A.F.); Department of Radiology, Duke University School of Medicine, Durham, NC (L.H.K., M.R.P.); Wakayama Medical University, Wakayama, Japan (H.M., T. Akasaka, H.K.); Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (B.L.N., J.M.J.); Department of Cardiology, University Hospital of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark (N.P.R.S.); Erasmus Medical Center, Rotterdam, the Netherlands (K.N.); Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.B.); Centro Cardiologico Monzino, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), University of Milan, Milan, Italy (G.P.); William Beaumont Hospital, Royal Oak, Mich (K.M.C.); Loyola University Medical Center, Maywood, Ill (M.G.R.); Aichi Medical University, Aichi, Japan (T. Amano); Department of Cardiology, Shin Koga Hospital, Fukuoka, Japan (T.K.); HeartFlow, Redwood City, Calif (C.R.); and University of Northern British Columbia, Prince George, British Columbia, Canada (G.W.P.).ORCID 0000-0002-3539-5730
University of British Columbia · CAWakayama Medical University · JPAarhus University Hospital · DKDuke University · USAichi Medical University · JPBeaumont Hospital, Royal Oak · USErasmus MC · NLHeartFlow (United States) · USKoga Hospital · JPLeiden University Medical Center · NLLoyola University Medical Center · USUniversity of Liverpool · GBUniversity of Milan · ITUniversity of Northern British Columbia · CAUniversity of Southern Denmark · DK
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose To examine the relationship between smoking status and coronary volume-to-myocardial mass ratio (V/M) among individuals with coronary artery disease (CAD) undergoing CT fractional flow reserve (CT-FFR) analysis. Materials and Methods In this secondary analysis, participants from the ADVANCE registry evaluated for suspected CAD from July 15, 2015, to October 20, 2017, who were found to have coronary stenosis of 30% or greater at coronary CT angiography (CCTA) were included if they had known smoking status and underwent CT-FFR and V/M analysis. CCTA images were segmented to calculate coronary volume and myocardial mass. V/M was compared between smoking groups, and predictors of low V/M were determined. Results The sample for analysis included 503 current smokers, 1060 former smokers, and 1311 never-smokers (2874 participants; 1906 male participants). After adjustment for demographic and clinical factors, former smokers had greater coronary volume than never-smokers (former smokers, 3021.7 mm
Indexed as
Coronary Artery DiseaseFractional Flow Reserve, MyocardialCoronary AngiographyFemaleHeartHumansMaleMyocardiumSmokingCardiacCT AngiographyHeartIschemia/Infarction
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