Evidence map›Paper›PMID 38483245›Full record

ArticleRadiology. Cardiothoracic imaging2024

Measurement Variability of Same-Day CT Quantification of Interstitial Lung Disease: A Multicenter Prospective Study.

Jong Hyuk Lee, Kum Ju Chae, Jimyung Park, Sun Mi Choi, Myoung-Jin Jang, Eui Jin Hwang, Gong Yong Jin, Jin Mo Goo

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A systematic review of the role of quantitative CT in the prognostication and disease monitoring of interstitial lung disease.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jong Hyuk Lee *From the Department of Radiology and Institute of Radiation Medicine (J.H.L., E.J.H., J.M.G.), Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine (J.P., S.M.C.), and Medical Research Collaborating Center (M.J.J.), Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea; Department of Radiology, Research Institute of Clinical Medicine of Jeonbuk National University Biomedical Research Institute of Jeonbuk National University Hospital, Jeonbuk National University and Medical School, Jeonju, Korea (K.J.C., G.Y.J.); Department of Radiology, National Jewish Health, Denver, Colo (K.J.C.); Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea (J.M.G.); and Cancer Research Institute, Seoul National University, Seoul, Korea (J.M.G.).ORCID 0000-0002-9594-683X
Kum Ju Chae *From the Department of Radiology and Institute of Radiation Medicine (J.H.L., E.J.H., J.M.G.), Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine (J.P., S.M.C.), and Medical Research Collaborating Center (M.J.J.), Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea; Department of Radiology, Research Institute of Clinical Medicine of Jeonbuk National University Biomedical Research Institute of Jeonbuk National University Hospital, Jeonbuk National University and Medical School, Jeonju, Korea (K.J.C., G.Y.J.); Department of Radiology, National Jewish Health, Denver, Colo (K.J.C.); Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea (J.M.G.); and Cancer Research Institute, Seoul National University, Seoul, Korea (J.M.G.).ORCID 0000-0003-3012-3530
Jimyung ParkFrom the Department of Radiology and Institute of Radiation Medicine (J.H.L., E.J.H., J.M.G.), Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine (J.P., S.M.C.), and Medical Research Collaborating Center (M.J.J.), Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea; Department of Radiology, Research Institute of Clinical Medicine of Jeonbuk National University Biomedical Research Institute of Jeonbuk National University Hospital, Jeonbuk National University and Medical School, Jeonju, Korea (K.J.C., G.Y.J.); Department of Radiology, National Jewish Health, Denver, Colo (K.J.C.); Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea (J.M.G.); and Cancer Research Institute, Seoul National University, Seoul, Korea (J.M.G.).ORCID 0000-0003-2655-5517
Sun Mi ChoiFrom the Department of Radiology and Institute of Radiation Medicine (J.H.L., E.J.H., J.M.G.), Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine (J.P., S.M.C.), and Medical Research Collaborating Center (M.J.J.), Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea; Department of Radiology, Research Institute of Clinical Medicine of Jeonbuk National University Biomedical Research Institute of Jeonbuk National University Hospital, Jeonbuk National University and Medical School, Jeonju, Korea (K.J.C., G.Y.J.); Department of Radiology, National Jewish Health, Denver, Colo (K.J.C.); Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea (J.M.G.); and Cancer Research Institute, Seoul National University, Seoul, Korea (J.M.G.).
Myoung-Jin JangFrom the Department of Radiology and Institute of Radiation Medicine (J.H.L., E.J.H., J.M.G.), Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine (J.P., S.M.C.), and Medical Research Collaborating Center (M.J.J.), Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea; Department of Radiology, Research Institute of Clinical Medicine of Jeonbuk National University Biomedical Research Institute of Jeonbuk National University Hospital, Jeonbuk National University and Medical School, Jeonju, Korea (K.J.C., G.Y.J.); Department of Radiology, National Jewish Health, Denver, Colo (K.J.C.); Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea (J.M.G.); and Cancer Research Institute, Seoul National University, Seoul, Korea (J.M.G.).ORCID 0000-0001-8123-5001
Eui Jin HwangFrom the Department of Radiology and Institute of Radiation Medicine (J.H.L., E.J.H., J.M.G.), Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine (J.P., S.M.C.), and Medical Research Collaborating Center (M.J.J.), Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea; Department of Radiology, Research Institute of Clinical Medicine of Jeonbuk National University Biomedical Research Institute of Jeonbuk National University Hospital, Jeonbuk National University and Medical School, Jeonju, Korea (K.J.C., G.Y.J.); Department of Radiology, National Jewish Health, Denver, Colo (K.J.C.); Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea (J.M.G.); and Cancer Research Institute, Seoul National University, Seoul, Korea (J.M.G.).ORCID 0000-0002-3697-5542
Gong Yong JinFrom the Department of Radiology and Institute of Radiation Medicine (J.H.L., E.J.H., J.M.G.), Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine (J.P., S.M.C.), and Medical Research Collaborating Center (M.J.J.), Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea; Department of Radiology, Research Institute of Clinical Medicine of Jeonbuk National University Biomedical Research Institute of Jeonbuk National University Hospital, Jeonbuk National University and Medical School, Jeonju, Korea (K.J.C., G.Y.J.); Department of Radiology, National Jewish Health, Denver, Colo (K.J.C.); Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea (J.M.G.); and Cancer Research Institute, Seoul National University, Seoul, Korea (J.M.G.).
Jin Mo GooFrom the Department of Radiology and Institute of Radiation Medicine (J.H.L., E.J.H., J.M.G.), Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine (J.P., S.M.C.), and Medical Research Collaborating Center (M.J.J.), Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea; Department of Radiology, Research Institute of Clinical Medicine of Jeonbuk National University Biomedical Research Institute of Jeonbuk National University Hospital, Jeonbuk National University and Medical School, Jeonju, Korea (K.J.C., G.Y.J.); Department of Radiology, National Jewish Health, Denver, Colo (K.J.C.); Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea (J.M.G.); and Cancer Research Institute, Seoul National University, Seoul, Korea (J.M.G.).ORCID 0000-0003-1791-7942

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose To investigate quantitative CT (QCT) measurement variability in interstitial lung disease (ILD) on the basis of two same-day CT scans. Materials and Methods Participants with ILD were enrolled in this multicenter prospective study between March and October 2022. Participants underwent two same-day CT scans at an interval of a few minutes. Deep learning-based texture analysis software was used to segment ILD features. Fibrosis extent was defined as the sum of reticular opacity and honeycombing cysts. Measurement variability between scans was assessed with Bland-Altman analyses for absolute and relative differences with 95% limits of agreement (LOA). The contribution of fibrosis extent to variability was analyzed using a multivariable linear mixed-effects model while adjusting for lung volume. Eight readers assessed ILD fibrosis stability with and without QCT information for 30 randomly selected samples. Results Sixty-five participants were enrolled in this study (mean age, 68.7 years ± 10 [SD]; 47 [72%] men, 18 [28%] women). Between two same-day CT scans, the 95% LOA for the mean absolute and relative differences of quantitative fibrosis extent were -0.9% to 1.0% and -14.8% to 16.1%, respectively. However, these variabilities increased to 95% LOA of -11.3% to 3.9% and -123.1% to 18.4% between CT scans with different reconstruction parameters. Multivariable analysis showed that absolute differences were not associated with the baseline extent of fibrosis (

Indexed as

Lung Diseases, InterstitialPulmonary FibrosisAgedFemaleHumansLinear ModelsMaleMiddle AgedProspective StudiesTomography, X-Ray ComputedComputer AssistedCTCT-QuantitativeDiagnosisDiagnostic ImagingInterstitialLungLung DiseasesPulmonary FibrosisThorax

Identifiers

PMID38483245
PMCPMC11056748

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.