Evidence map›Paper›PMID 38483241›Full record

ArticleJournal of the European Academy of Dermatology and Venereology : JEADV2024

Dermatoscopic patterns of cutaneous metastases: A multicentre cross-sectional study of the International Dermoscopy Society.

Danica Tiodorovic, Jelena Stojkovic-Filipovic, Ashfaq Marghoob, Giuseppe Argenziano, Susana Puig, Josep Malvehy, Linda Tognetti, Rubegni Pietro, Bengu Nisa Akay, Iris Zalaudek and 32 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Journal of the European Academy of Dermatology and Venereology : JEADV, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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  12. Diagnosis and Management of Scalp Metastases: A Review.Diagnostics (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors at 20 institutions in 17 countries.

Danica TiodorovicClinic of Dermatovenerology, University Clinical Center of Nis, Medical Faculty, University of Nis, Nis, Serbia.ORCID https://orcid.org/0000-0002-1157-1402
Jelena Stojkovic-FilipovicClinic of Dermatology and Venereology, University Clinical Center of Serbia, Faculty of Medicine, Department of Dermatology and Venereology, University of Belgrade, Belgrade, Serbia.ORCID https://orcid.org/0000-0002-7762-3199
Ashfaq MarghoobMemorial Sloan Kettering Cancer Center, Uniondale, New York, USA.
Giuseppe ArgenzianoDermatology Unit, University of Campania, Naples, Italy.ORCID https://orcid.org/0000-0003-1413-8214
Susana PuigDermatology Department, Hospital Clinic Barcelona, IDIBAPS, University of Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0003-1337-9745
Josep MalvehyDermatology Department, Hospital Clinic Barcelona, IDIBAPS, University of Barcelona, Barcelona, Spain.
Linda TognettiDermatology Unit, Department of Medical, Surgical and Neurosciences, University of Siena, Siena, Italy.ORCID https://orcid.org/0000-0002-6691-4310
Rubegni PietroDermatology Unit, Department of Medical, Surgical and Neurosciences, University of Siena, Siena, Italy.
Bengu Nisa AkayMedicine Faculty Department of Dermatology, Ankara University, Ankara, Turkey.ORCID https://orcid.org/0000-0002-4896-1666
Iris ZalaudekDepartment of Dermatology and Venerology, Medical University of Trieste, Trieste, Italy.
Holger A HaenssleDepartment of Dermatology, University of Heidelberg, Heidelberg, Germany.ORCID https://orcid.org/0000-0001-7255-3104
Christine Müller-ChristmannDepartment of Dermatology, University of Heidelberg, Heidelberg, Germany.
Elisa CinottiDermatology Unit, Department of Medical, Surgical and Neurosciences, University of Siena, Siena, Italy.ORCID https://orcid.org/0000-0002-4009-0659
Jean Luc PerrotDepartment of Dermatology, CHU Saint Etienne, Saint-Etienne, France.
Pedro ZaballosDermatology Department, Hospital de Sant Pau i Santa Tecla, Tarragota, Spain.
Renato Marchiori BakosDepartment of Dermatology, Hospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul-Porto Alegre, Porto Alegre, Brazil.
Luc ThomasDepartment of Dermatology, Centre Hospitalier Lyon Sud, Lyons Cancer Research Center, Lyon 1 University, Lyon, France.ORCID https://orcid.org/0000-0003-1995-2434
Ketty PerisDermatologia, Dipartimento di Medicina e Chirurgia Traslazionale, UOC di Dermatologia, Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID https://orcid.org/0000-0003-1957-6600
Aimilios LallasFirst Department of Dermatology, School of Medicine, Faculty of Health Sciences, Aristotle University, Thessaloniki, Greece.ORCID https://orcid.org/0000-0002-7193-0964
Zoe ApallaFirst Department of Dermatology, School of Medicine, Faculty of Health Sciences, Aristotle University, Thessaloniki, Greece.ORCID https://orcid.org/0000-0002-9255-8196
Juergen F KreuschPrivate Dermatological Practice, Luebeck, Germany.
Isabelle TrommeDepartment of Dermatology and Melanoma Clinic St Luc Hospital, Catholic, University of Louvain, Brussels, Belgium.
Alexandros J StratigosAndreas Sygros Hospital for Cutaneous and Venereal Diseases, Athens, Greece.
Maria Antonietta PizzichettaDepartment of Dermatology, University of Trieste, Aviano, Italy.ORCID https://orcid.org/0000-0002-4201-8490
Lidija KandolfDepartment of Dermatology and Venereology, Faculty of Medicine, Military Medical Academy, Belgrade, Serbia.ORCID https://orcid.org/0000-0002-5221-5068
Caterina LongoDepartment of Dermatology, University of Modena and Reggio Emili, Modena, Italy.ORCID https://orcid.org/0000-0002-8218-3896
Andreas BlumPublic, Private and Teaching Practice of Dermatology, Konstanz, Germany.
Masaru TanakaDepartment of Dermatology, Tokyo Women's Medical University Adachi Medical Center, Tokyo, Japan.
Rainer Hofmann-WellenhofDepartment of Dermatology and Venerology, Medical University Graz, Graz, Austria.
Andrija JovicClinic of Dermatovenerology, University Clinical Center of Nis, Nis, Serbia.ORCID https://orcid.org/0000-0002-7943-0622
John PaoliDepartment of Dermatology and Venereology, Institute of Clinical Sciences, Sahlgrenska Academy, Region Västra Götaland, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0000-0003-1326-8535
Marija BuljanDepartment of Dermatology and Venereology, Sestre Milosrdnice University Hospital Centre, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.
Martina Espasandín-AriasDepartment of Dermatology, University Hospital of Pontevedra, Pontevedra, Spain.
Horacio CaboUniversity of Buenos Aires, Buenos Aires, Argentina.
Sonia Rodrigiez SaaDepartment of Dermatology, Hospital Del Carmen, Mendoza, Argentina.
Gabriel SalerniDepartment of Dermatology, Hospital Provincial del Centenario, National University of Rosario, Rosario, Argentina.
Gianluca NazzaroDermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.ORCID https://orcid.org/0000-0001-8534-6497
Grazyna Kaminska-WinciorekDepartment of Bone Marrow Transplantation and Hematology-Oncology; Skin Cancer and Melanoma Team, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice, Poland.
Giovanni DamianiItalian Center of Precisione Medicine and Chronic Inflammation Milan, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
Franciska GesztiSmartderm Medical Office, Budapest, Hungary.
Harald KittlerDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.
IDS Study group
University of Siena · ITAristotle University of Thessaloniki · GRHeidelberg University · DEHospital Clínic de Barcelona · ESUniversity of Nis · RSUniversity of Trieste · ITAndreas Sygros Hospital · GRAnkara University · TRApple (Israel) · ILCentre Hospitalier Universitaire de Saint-Étienne · FRComplejo Hospitalario de Pontevedra · ESFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITHospital de Sant Pau · ESKlinikum Konstanz · DEMedical University of Graz · ATMedical University of Vienna · ATMemorial Sloan Kettering Cancer Center · USMilitary Medical Academy · RSNational University of Rosario · ARSahlgrenska University Hospital · SE

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundThe detection of cutaneous metastases (CMs) from various primary tumours represents a diagnostic challenge.

objectivesOur aim was to evaluate the general characteristics and dermatoscopic features of CMs from different primary tumours.

methodsRetrospective, multicentre, descriptive, cross-sectional study of biopsy-proven CMs.

resultsWe included 583 patients (247 females, median age: 64 years, 25%-75% percentiles: 54-74 years) with 632 CMs, of which 52.2% (n = 330) were local, and 26.7% (n = 169) were distant. The most common primary tumours were melanomas (n = 474) and breast cancer (n = 59). Most non-melanoma CMs were non-pigmented (n = 151, 95.6%). Of 169 distant metastases, 54 (32.0%) appeared on the head and neck region. On dermatoscopy, pigmented melanoma metastases were frequently structureless blue (63.6%, n = 201), while amelanotic metastases were typified by linear serpentine vessels and a white structureless pattern. No significant difference was found between amelanotic melanoma metastases and CMs of other primary tumours.

conclusionsThe head and neck area is a common site for distant CMs. Our study confirms that most pigmented melanoma metastasis are structureless blue on dermatoscopy and may mimic blue nevi. Amelanotic metastases are typified by linear serpentine vessels and a white structureless pattern, regardless of the primary tumour.

Indexed as

DermoscopyMelanomaSkin NeoplasmsAdultAgedBreast NeoplasmsCross-Sectional StudiesFemaleHead and Neck NeoplasmsHumansMaleMiddle AgedRetrospective Studies

Identifiers

PMID38483241
PMCPMC11630489
OpenAlexW4392805036

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.