Evidence map›Paper›PMID 38483074›Full record

ArticleJournal of veterinary internal medicine

Prevalence, clinical presentation, and etiology of myelopathies in 224 juvenile dogs.

Ed J Pilkington, Steven De Decker, Eleftheria Skovola, Ana Cloquell Miro, Rodrigo Gutierrez Quintana, Kiterie M E Faller, Albert Aguilera Padros, Rita Goncalves

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ed J PilkingtonSmall Animal Teaching Hospital, Institute of Veterinary Science, University of Liverpool, Liverpool, United Kingdom.ORCID https://orcid.org/0000-0002-6296-0256
Steven De DeckerDepartment of Clinical Science and Services, Royal Veterinary College, University of London, Hatfield, United Kingdom.ORCID https://orcid.org/0000-0002-2505-2152
Eleftheria SkovolaDepartment of Clinical Science and Services, Royal Veterinary College, University of London, Hatfield, United Kingdom.
Ana Cloquell MiroSmall Animal Hospital, School of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow, United Kingdom.
Rodrigo Gutierrez QuintanaSmall Animal Hospital, School of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow, United Kingdom.ORCID https://orcid.org/0000-0002-3570-2542
Kiterie M E FallerThe Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Midlothian, United Kingdom.ORCID https://orcid.org/0000-0002-4525-7059
Albert Aguilera PadrosThe Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Midlothian, United Kingdom.
Rita GoncalvesSmall Animal Teaching Hospital, Institute of Veterinary Science, University of Liverpool, Liverpool, United Kingdom.ORCID https://orcid.org/0000-0001-5420-9801
Roslin Institute · GBUniversity of Glasgow · GBUniversity of Liverpool · GBUniversity of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntervertebral disc herniation is widely recognized as the most common cause of myelopathy in dogs older than 2 years; however, the prevalence of various causes of myelopathy in younger dogs has not been reported. HYPOTHESIS/

objectivesTo describe the prevalence, clinical presentation, and etiology of myelopathy in dogs aged 18 months or less. Secondarily, to investigate which clinical features were associated with each of the most common etiologies. ANIMALS: Two hundred twenty-four dogs aged 18 months or less with myelopathy were included in the study.

methodsRetrospective review of clinical records from 4 referral institutions. Multivariable logistic regression analyses assessed which clinical features were associated with each diagnosis.

resultsFrench bulldogs (n = 51, 22.8%), pugs (n = 18, 8.0%), crossbreeds (n = 12, 5.4%), and English bulldogs (n = 11, 4.9%) were the most frequently affected breeds. Overall, 31 diagnoses were reached. The 5 most frequent diagnoses were vertebral malformation (VM; n = 42, 18.8%), spinal arachnoid diverticulum (SAD; n = 28, 12.5%), traumatic fracture of the vertebral column (n = 22, 9.8%), atlantoaxial instability (n = 18, 8.0%), and osseous-associated cervical spondylomyelopathy (n = 17, 7.6%). Intervertebral disc extrusion (IVDE) accounted for 4.5% of cases (n = 10). A final diagnosis of VM was associated with younger, screw-tailed, and pug breeds with chronic signs of T3-L3 myelopathy. SAD was associated with screw-tailed and pug breeds with nonpainful clinical signs. Intervertebral disc extrusion was associated with older, screw-tailed, and pug breeds with shorter duration of clinical signs. CONCLUSIONS AND CLINICAL IMPORTANCE: Prioritization of differential diagnoses for dogs presenting with signs of myelopathy when aged 18 months or less should differ to those for older dogs, with IVDE not the most common cause in the former.

Indexed as

Dog DiseasesSpinal Cord DiseasesAnimalsDogsFemaleIntervertebral Disc DisplacementMalePrevalenceRetrospective Studiesdiverticulummalformationscrew‐tailspinal

Identifiers

PMID38483074
PMCPMC11099773
OpenAlexW4392817772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.