ArticleAnnals of clinical and translational neurology2024
Nicolau syndrome following glatiramer acetate for multiple sclerosis: Case and review of reports.
Article in Annals of clinical and translational neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
- Nicolau syndrome in a pediatric patient after corticosteroid injection: a case report and review of the literature.Journal of medical case reports · 2025Review
- Nicolau Syndrome following Benzathine Benzylpenicillin Injection in a Patient with Syphilis and Type 2 Diabetes: A Case Report.Case reports in dermatologyArticle
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nicolau syndrome is a rare, iatrogenic skin reaction after parental drug administration, characterized by severe pain at an injection site, followed by hemorrhage, ulceration, and often necrosis. We present a case of a patient on glatiramer acetate for many years (initially Copaxone then Glatopa) who developed Nicolau syndrome, the second reported case after generic glatiramer acetate. All reported cases of Nicolau syndrome after glatiramer acetate are reviewed. The case highlights the importance of prompt recognition of this skin reaction by neurologists and raises awareness of the risks of skin reactions even in low-risk injectable DMTs.
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