Evidence map›Paper›PMID 38482619›Full record

ArticleAnti-cancer agents in medicinal chemistry2024

Investigating the Effects of

Mahsa Hatami Shandi, Shamim Sahranavard, Fereshteh Bagheri, Zahra Shahsavari, Siamak Salami

Abstract read
PubMed Publisher
In one paragraph

Article in Anti-cancer agents in medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mahsa Hatami ShandiDepartment of Clinical Biochemistry, Shahid Beheshti University of Medical Science, Tehran, Iran.ORCID 0009-0002-9862-5633
Shamim SahranavardTraditional Medicine and Materia Medical Research Center, Department of Traditional Pharmacy, School of Traditional Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran.
Fereshteh BagheriDepartment of Clinical Biochemistry, Shahid Beheshti University of Medical Science, Tehran, Iran.ORCID 0009-0000-6682-8888
Zahra ShahsavariDepartment of Clinical Biochemistry, Shahid Beheshti University of Medical Science, Tehran, Iran.ORCID 0000-0002-4451-7525
Siamak SalamiDepartment of Clinical Biochemistry, Shahid Beheshti University of Medical Science, Tehran, Iran.ORCID 0000-0003-0393-5058
Shahid Beheshti University · IR

Funding

Shahid Beheshti University of Medical Science of Iran 01-27526
6 · The paper itself

Abstract

backgroundDespite remarkable advances, cancer has remained the second cause of death, which shows that more potent novel compounds should be found. Ethnobotanical compounds have a long history of treating diseases, and several approved chemotherapeutic compounds were isolated from plants.

objectiveThe research aimed to evaluate the cytotoxic effects of

methodsCytotoxic effects of alcoholic, dichloromethane, and petroleum ether fractions of

resultsMethanolic extract exhibited the highest cytotoxicity, impacting A2780CP and MDA-MB-231. All fractions showed comparable effects on U251 cells. Notably, extracts displayed higher IC

conclusion

Indexed as

Antineoplastic Agents, PhytogenicApoptosisBreast NeoplasmsCell ProliferationDose-Response Relationship, DrugDrug Screening Assays, AntitumorGlioblastomaOvarian NeoplasmsPlant ExtractsPlant RootsCell SurvivalFemaleHumansMolecular StructureReactive Oxygen SpeciesStructure-Activity RelationshipAntineoplastic Agents, PhytogenicPlant ExtractsReactive Oxygen Speciesapoptosiscis-platin resistant ovarian cancerDorema hyrcanum.. Glioblastomaprogrammed cell deathtriple-negative breast cancer

Identifiers

PMID38482619
OpenAlexW4392811833

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.