Evidence map›Paper›PMID 38482556›Full record

ArticleAmerican journal of physiology. Renal physiology2024

Mice with a

Joanna Cunanan, Sarada Sriya Rajyam, Bedra Sharif, Khalil Udwan, Akanchaya Rana, Vanessa De Gregorio, Samantha Ricardo, Andrew Elia, Brian Brooks, Astrid Weins and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. [Treatment and Prospects of Focal Segmental Glomerulosclerosis].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Review
  3. Kidney international reports · 2025
    Article
  4. Mechanisms of podocyte injury in genetic kidney disease.Pediatric nephrology (Berlin, Germany) · 2025
    Review
  5. Review
  6. Podocytes in health and glomerular disease.Frontiers in cell and developmental biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Joanna CunananDivision of Nephrology, University Health Network, Toronto, Ontario, Canada.ORCID 0000-0001-9587-4533
Sarada Sriya RajyamDivision of Nephrology, University Health Network, Toronto, Ontario, Canada.
Bedra SharifDivision of Nephrology, University Health Network, Toronto, Ontario, Canada.
Khalil UdwanDivision of Nephrology, University Health Network, Toronto, Ontario, Canada.ORCID 0000-0002-6488-2757
Akanchaya RanaDivision of Nephrology, University Health Network, Toronto, Ontario, Canada.
Vanessa De GregorioDivision of Nephrology, University Health Network, Toronto, Ontario, Canada.ORCID 0009-0007-5873-3919
Samantha RicardoDivision of Nephrology, University Health Network, Toronto, Ontario, Canada.
Andrew EliaDepartment of Pathology, Princess Margaret Hospital, Toronto, Ontario, Canada.
Brian BrooksOphthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States.
Astrid WeinsDepartment of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States.
Martin PollakDivision of Nephrology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States.
Rohan JohnDepartment of Pathology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.
Moumita BaruaDivision of Nephrology, University Health Network, Toronto, Ontario, Canada.ORCID 0000-0003-0628-9071
University Health Network · CABeth Israel Deaconess Medical Center · USBrigham and Women's Hospital · USNational Institutes of Health · USPrincess Margaret Cancer Centre · CAUniversity of Toronto · CA

Funding

Canadian Government | Canadian Institutes of Health Research (CIHR) 175145Frederick Banting and Charles Best Canada Graduate Scholarships - Doctoral Award
6 · The paper itself

Abstract

PAX2 regulates kidney development, and its expression persists in parietal epithelial cells (PECs), potentially serving as a podocyte reserve. We hypothesized that mice with a

Indexed as

DoxorubicinKidney GlomerulusMutation, MissensePAX2 Transcription FactorPodocytesAnimalsApoptosisCell ProliferationDisease Models, AnimalKidney DiseasesMaleMiceMice, Inbred C57BLPhenotypeRegenerationDoxorubicinPax2 protein, mousePAX2 Transcription Factorglomerular repairparietal epithelial cellsPAX2podocyteregeneration

Identifiers

PMID38482556
PMCPMC12040299
OpenAlexW4392823628

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.