Evidence map›Paper›PMID 38482554›Full record

ArticleAmerican journal of physiology. Renal physiology2024

Predicting sex differences in the effects of diuretics in renal epithelial transport during angiotensin II-induced hypertension.

Kaixin Zheng, Anita T Layton

Open access · greenAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kaixin ZhengDepartment of Applied Mathematics, University of Waterloo, Waterloo, Ontario, Canada.ORCID 0009-0005-7146-6988
Anita T LaytonDepartment of Applied Mathematics, University of Waterloo, Waterloo, Ontario, Canada.ORCID 0000-0002-1753-4063
University of Waterloo · CA

Funding

Canadian Government | NSERC | RES'EAU-WaterNET RGPIN-2019-03916
6 · The paper itself

Abstract

Chronic angiotensin II (ANG II) infusion is an experimental model that induces hypertension in rodents. The natriuresis, diuresis, and blood pressure responses differ between males and females. This is perhaps not unexpected, given the rodent kidney, which plays a key role in blood pressure regulation, exhibits marked sex differences. Under normotensive conditions, compared with males, the female rat nephron exhibits lower Na

Indexed as

Angiotensin IIHypertensionNatriuresisSodium-Hydrogen Exchanger 3AnimalsBlood PressureComputer SimulationDisease Models, AnimalDiuresisDiureticsFemaleKidneyMaleRatsSex CharacteristicsSex FactorsAngiotensin IIDiureticsSlc9a3 protein, ratSodiumSodium Chloride Symporter InhibitorsSodium-Hydrogen Exchanger 3Sodium Potassium Chloride Symporter Inhibitorsangiotensin IIdiureticselectrolyte transporthypertensionsex differences

Identifiers

PMID38482554
PMCPMC11918343
OpenAlexW4392812945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.