Evidence map›Paper›PMID 38482425›Full record

ArticleTranslational cancer research2024

The impact of alpha-1 antitrypsin deficiency alleles on lung cancer survival.

José María Hernández-Pérez, Carolina Ramos-Izquierdo, Juan Marco Figueira-Gonçalves, Francisco Martínez-Bugallo, Yolanda Ramallo-Fariña, Lorenzo Pérez-Negrín

Open access · diamondAbstract read
In one paragraph

Article in Translational cancer research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

José María Hernández-PérezRespiratory Medicine, University Hospital "Nuestra Señora de Candelaria", Santa Cruz de Tenerife, Spain.
Carolina Ramos-IzquierdoRespiratory Medicine, University Hospital "Nuestra Señora de Candelaria", Santa Cruz de Tenerife, Spain.
Juan Marco Figueira-GonçalvesRespiratory Medicine, University Hospital "Nuestra Señora de Candelaria", Santa Cruz de Tenerife, Spain.
Francisco Martínez-BugalloGenetics Unit, Clinical Analysis Department, University Hospital "Nuestra Señora de Candelaria", Santa Cruz de Tenerife, Spain.
Yolanda Ramallo-FariñaCanary Foundation Health Research Institute of the Canary Islands (FIISC), Santa Cruz de Tenerife, Spain.
Lorenzo Pérez-NegrínRespiratory Medicine, University Hospital "Nuestra Señora de Candelaria", Santa Cruz de Tenerife, Spain.
Hospital Universitario Nuestra Señora de Candelaria · ESRed de Investigación en Actividades Preventivas y Promoción de la Salud · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Different studies have shown that carrying an alpha-1 antitrypsin (AAT) deficiency allele is an independent risk factor for developing lung cancer (LC). However, to date, little is known regarding whether carrying a deficiency allele may be a prognostic factor in the evolution of LC. A prospective observational study was carried out which consecutively included patients diagnosed with LC in University Hospital "Nuestra Señora de Candelaria" between December 2017 and August 2020. A blood sample was taken from each of the patients in order to determine both AAT serum concentration and genotype. Based on AAT genotype, patients were divided into the deficiency (

Indexed as

alpha-1 antitrypsin (AAT)alpha-1 antitrypsin deficiency (AAT deficiency)Lung cancer (LC)mortalityneoplasia

Identifiers

PMID38482425
PMCPMC10928642
OpenAlexW4392301012

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.