ArticleBrain communications2024
Predicting functional decline in aging and Alzheimer's disease with PET-based Braak staging.
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Article in Brain communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
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Who cites it
17 citing papers in PubMed, 13 citations in OpenAlex.
- Multimodal prognostic modeling of individual cognitive trajectories to enhance trial efficiency in preclinical Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Trial
- Data-driven thresholds for standardized classification of severe Alzheimer's disease neuropathology using digital neuropathology.Brain pathology (Zurich, Switzerland) · 2026Article
- Tau-PET correlates of mild behavioral impairment in preclinical and prodromal Alzheimer's disease: A head-to-head comparison of Flortaucipir and MK6240.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Classification of tau status with machine learning models in amyloid-positive cohorts.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Visual versus quantitative tau-PET Braak staging in Alzheimer's disease using [European journal of nuclear medicine and molecular imaging · 2026Article
- Spatiotemporal dynamics of tau extent and load increase in Alzheimer's disease across four longitudinal cohorts.Nature aging · 2026Article
- Impact of reducedEJNMMI physics · 2026Article
- Tau extent outperforms tau load as a predictor of neurodegeneration in Alzheimer's disease.Molecular neurodegeneration · 2026Article
- Language deficits across PET-based Braak stages of tau accumulation in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- PolyGR-containing aggregates link with pathology and clinical features of Alzheimer's disease.Acta neuropathologica · 2025Article
- Glia inflammation and cell death pathways drive disease progression in preclinical and early AD.EMBO molecular medicine · 2025Article
- Rates of clinical progression according to biological Alzheimer's disease stages.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- The Evolution of Randomized Clinical Trial Designs to Assess Therapeutics in Alzheimer Disease.JAMA network open · 2025Article
- Temporal Muscle Thickness as a New Biomarker: Its Association With Alzheimer Pathology and Cognitive Impairment in Chinese Adults.Journal of cachexia, sarcopenia and muscle · 2025Article
- The impact of tau-PET in a selected memory clinic cohort: rationale and design of the TAP-TAU study.Alzheimer's research & therapy · 2024Article
- Natural Compounds for Preventing Age-Related Diseases and Cancers.International journal of molecular sciences · 2024Review
- Survey among experts on the future role of tau-PET in clinical practice and trials.Alzheimer's & dementia (Amsterdam, Netherlands)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors at 5 institutions in 4 countries.
Arthur C MacedoTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.
Joseph TherriaultTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.
Cécile TissotTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.
Jaime Fernandez-AriasTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.ORCID https://orcid.org/0000-0002-6810-5920
Pamela C L FerreiraDepartment of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15213, USA.ORCID https://orcid.org/0000-0003-2134-9829
Paolo VitaliTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.ORCID https://orcid.org/0000-0001-8953-1542
Stijn ServaesTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.
Nesrine RahmouniTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.
Marie VermeirenTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.
Gleb BezginTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.
Firoza Z LussierTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.
Jenna StevensonTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.
Yi-Ting WangTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.ORCID https://orcid.org/0000-0002-9130-5461
Kely Quispialaya SocualayaTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.
Peter KunachTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.
Tahnia NazneenTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.
Seyyed Ali HosseiniTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.
Vanessa PallenTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.
Alyssa StevensonTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.
João Pedro Ferrari-SouzaDepartment of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
Bruna BellaverDepartment of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
Douglas Teixeira LeffaDepartment of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
Kok Pin NgDepartment of Neurology, National Neuroscience Institute, Singapore, 308433, Singapore.
Eduardo R ZimmerTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.ORCID https://orcid.org/0000-0002-5349-0053
Tharick A PascoalDepartment of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
Serge GauthierTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.
Pedro Rosa-NetoTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Mental Health Institute, Montreal, Quebec, H4H 1R3, Canada.ORCID https://orcid.org/0000-0001-9116-1376
Montreal Neurological Institute and Hospital · CAUniversity of Pittsburgh · USDouglas Mental Health University Institute · CANational Neuroscience Institute · SGUniversidade Federal do Rio Grande do Sul · BR
Funding
No grant is acknowledged in the PubMed record.
Abstract
The progression of PET-based Braak stages correlates with cognitive deterioration in aging and Alzheimer's disease. Here, we investigate the association between PET-based Braak stages and functional impairment and assess whether PET-based Braak staging predicts a longitudinal decline in the performance of activities of daily living. In this cohort study, we evaluated cognitively unimpaired individuals and individuals with mild cognitive impairment or Alzheimer's disease dementia. Participants underwent [
Indexed as
activities of daily livingAlzheimer’s diseaseBraak stagesneurofibrillary tanglesPET
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.