Evidence map›Paper›PMID 38482316›Full record

ArticleJournal of family medicine and primary care2024

Comparative analysis of CBNAAT (GeneXpert) and Ziehl-Nielsen staining test as diagnostic modalities of tuberculosis.

Priyanka Yadav, Priyanka Mahour, Aditi Agarwal, Amit Garg

Open access · goldAbstract read
In one paragraph

Article in Journal of family medicine and primary care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Why CBNAAT not called as gold standard test for TB?Journal of family medicine and primary care · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Priyanka YadavDepartment of Microbiology, Lala Lajpat Rai Memorial Medical College, Meerut, Uttar Pradesh, India.
Priyanka MahourDepartment of Microbiology, Lala Lajpat Rai Memorial Medical College, Meerut, Uttar Pradesh, India.
Aditi AgarwalDepartment of Microbiology, Lala Lajpat Rai Memorial Medical College, Meerut, Uttar Pradesh, India.
Amit GargDepartment of Microbiology, Lala Lajpat Rai Memorial Medical College, Meerut, Uttar Pradesh, India.
Lala Lajpat Rai Memorial Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: As centuries and millennia passed, tuberculosis remains the major health threat for millions of people. Due to this resurgence of tuberculosis, scientists around the globe have intensified their research efforts to curb down the transmission of this disease and that is the reason which led to the development of new and efficient diagnostic tools, one such being the rapid cartridge-based nucleic acid amplification test which can give the real-time results and that too in a short period of time. These diagnostic tools which are based on the latest technologies help in paving the way to eliminate tuberculosis by early detection method and further prevent the transmission. Aim: In this study, we did a comparative analysis of the effectiveness of CBNAAT technique in the early detection of Materials and Methods: Comparative analysis of CBNAAT (GeneXpert) and Ziehl-Nielsen staining test was done as diagnostic modalities using standard protocols. Results: Out of total 300 samples, 153 were female, 146 were male, while one was transgender. For all these samples, the positivity rates were 48% for the CBNAAT technique and 21.3% for ZN staining method, respectively. For extrapulmonary samples, positivity rates were 49.1% and 11.86% for CBNAAT and ZN microscopy, respectively, while the same for pulmonary samples was 47.7% and 23.6%, respectively. Conclusions: ZN microscopy and CBNAAT are both initial tests for the detection of

Indexed as

CBNAATextrapulmonary tuberculosisMDR tuberculosisPulmonary tuberculosisTuberculosisZiehl–Nielsen staining

Identifiers

PMID38482316
PMCPMC10931856
OpenAlexW4391660463

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.