Evidence map›Paper›PMID 38482249›Full record

ArticleJournal of gastrointestinal oncology2024

Immune checkpoint blockade induced sarcoid-like reaction mimicking progression of disease in a patient with microsatellite instable colorectal cancer: case report and review of the literature.

Fergus Keane, Elizabeth Yogiaveetil, Brie Kezlarian, Maria Lagratta, Neil H Segal, Ghassan Abou-Alfa, Eileen M O'Reilly, Leonard Saltz, Imane El Dika

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Journal of gastrointestinal oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Fergus KeaneDepartment of Gastrointestinal Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Elizabeth YogiaveetilDepartment of Respiratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Brie KezlarianDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Maria LagrattaDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Neil H SegalDepartment of Gastrointestinal Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Ghassan Abou-AlfaDepartment of Gastrointestinal Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Eileen M O'ReillyDepartment of Gastrointestinal Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Leonard SaltzDepartment of Gastrointestinal Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Imane El DikaDepartment of Gastrointestinal Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Memorial Sloan Kettering Cancer Center · USCornell University · USTrinity College Dublin · IE

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Background: Oncologists are prescribing checkpoint inhibitors with greater frequency, and an awareness of and ability to recognize immune-related adverse events (irAEs) is a key part of the safe administration of these drugs. Case Description: Herein, we report the case of a 26-year-old male diagnosed with Conclusions: This case highlights the propensity of SLRs to imitate progression of disease, and the importance of awareness of this adverse effect, to prompt appropriate investigation and management.

Indexed as

case reportimmune checkpoint blockade (ICB)Lynch syndromePembrolizumabsarcoid-like reaction (SLR)

Identifiers

PMID38482249
PMCPMC10932687
OpenAlexW4391567415

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.