Evidence map›Paper›PMID 38482235›Full record

ArticleJournal of gastrointestinal oncology2024

Prospective comparison of positron emission tomography (PET)/magnetic resonance and PET/computed tomography dosimetry in hepatic malignant neoplastic disease after

Ram Gurajala, Sasan Partovi, Frank P DiFilippo, Xin Li, Christopher Coppa, Shetal N Shah, Karunakaravel Karuppasamy, Nancy Obuchowski, Ehsan Fayazzadeh, Gordon McLennan and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of gastrointestinal oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Ram GurajalaSection of Interventional Radiology, Imaging Institute, Cleveland Clinic Main Campus, Cleveland, Ohio, USA.
Sasan PartoviSection of Interventional Radiology, Imaging Institute, Cleveland Clinic Main Campus, Cleveland, Ohio, USA.
Frank P DiFilippoDepartment of Nuclear Medicine, Imaging Institute, Cleveland Clinic Main Campus, Cleveland, Ohio, USA.
Xin LiDepartment of Radiology, Hospital of The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Christopher CoppaSection of Abdominal Imaging, Imaging Institute, Cleveland Clinic Main Campus, Cleveland, Ohio, USA.
Shetal N ShahDepartment of Nuclear Medicine, Imaging Institute, Cleveland Clinic Main Campus, Cleveland, Ohio, USA.
Karunakaravel KaruppasamySection of Interventional Radiology, Imaging Institute, Cleveland Clinic Main Campus, Cleveland, Ohio, USA.
Nancy ObuchowskiDepartment of Quantitative Health Sciences, Cleveland Clinic Main Campus, Cleveland, Ohio, USA.
Ehsan FayazzadehDepartment of Radiology, Saint Louis University Hospital, St. Louis, Missouri, USA.
Gordon McLennanSection of Interventional Radiology, Department of Radiology, University of Colorado Anschutz Medical Campus, Denver, Colorado, USA.
Abraham LevitinSection of Interventional Radiology, Imaging Institute, Cleveland Clinic Main Campus, Cleveland, Ohio, USA.
Cleveland Clinic · USHospital of the University of Pennsylvania · USSaint Louis University Hospital · USUniversity of Colorado Anschutz Medical Campus · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: In this single-institution study, 18 patients (20 treatment sessions) with a primary or metastatic hepatic malignancy underwent both PET/MR and PET/CT after Results: PET/MR underestimated tumor and liver absorbed doses when compared to PET/CT by -3.7% (P=0.042) and -5.8% (P=0.029), respectively. A coverage probability plot demonstrated that 80% and 90% of tumor dose measurements fell within intermodality differences of 11% and 18%, respectively. PET/MR underestimated tumor dose at both low (<1 GBq) and high (>3 GBq) injected activity levels (P<0.001) by -22.3 [standard deviation (SD) =13.5] and -24.3 (SD =18.7), respectively. Conclusions: Although PET/MR significantly underestimated the absorbed dose when compared to PET/CT, the intermodality agreement was high and the degree of underestimation was better than previously reported. Intermodality differences were more pronounced at low and high injected doses. Additional studies are required to assess the clinical implications of these findings.

Indexed as

90Y dosimetryhepatic malignancyPET/computed tomography (PET/CT)Positron emission tomography (PET)/magnetic resonance (MR)radioembolization

Identifiers

PMID38482235
PMCPMC10932664
OpenAlexW4392301563

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.