Evidence map›Paper›PMID 38482171›Full record

ArticleFrontiers in veterinary science2024

Sodium butyrate impedes the lymphoma caused by Marek's disease virus via regulating the mitochondrial apoptosis pathway.

Qiaoer Lin, Jun Zhou, Fan Yang, Congsen Zheng, Meiting Chen, Chuanzhe Chang, Shikai Cai, Feng Wen, Nina Wang, Yanfeng Chen and 1 more

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qiaoer LinSchool of Life Science and Engineering, Foshan University, Foshan, China.
Jun Zhou *School of Life Science and Engineering, Foshan University, Foshan, China.
Fan Yang *School of Life Science and Engineering, Foshan University, Foshan, China.
Congsen ZhengSchool of Life Science and Engineering, Foshan University, Foshan, China.
Meiting ChenSchool of Life Science and Engineering, Foshan University, Foshan, China.
Chuanzhe ChangSchool of Life Science and Engineering, Foshan University, Foshan, China.
Shikai CaiSchool of Life Science and Engineering, Foshan University, Foshan, China.
Feng WenSchool of Life Science and Engineering, Foshan University, Foshan, China.
Nina WangSchool of Life Science and Engineering, Foshan University, Foshan, China.
Yanfeng ChenSchool of Life Science and Engineering, Foshan University, Foshan, China.
Limei QinSchool of Life Science and Engineering, Foshan University, Foshan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sodium butyrate (NaB) has garnered attention in recent years for its ability to impede the malignant progression of tumors. In order to explore the potential inhibitory effects of NaB on the replication of Marek's disease virus (MDV) and subsequent lymphoma formation, newly hatched chickens were infected with the vvMDV Md5 strain and administered NaB prior to (prevention group) or following (treatment group) Md5 inoculation. The results revealed that NaB played a pivotal role in diminishing both the incidence and fatality rates in chickens afflicted with Md5 infection. Notably, NaB exhibited a remarkable capacity to inhibit the expression of MDV immediate early genes, i.e.,

Indexed as

apoptosisICP4latencylymphomaMDVmitochondrionsodium butyrate

Identifiers

PMID38482171
PMCPMC10932986

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.