Evidence map›Paper›PMID 38481664›Full record

ArticleFrontiers in cellular and infection microbiology2024

Molecular epidemiology of multidrug-resistant

John Osei Sekyere, Masego Mmatli, Anel Bosch, Ramathetje Virginia Ntsoane, Harishia Naidoo, Sinenhlanhla Doyisa, Nontuthuko E Maningi, Nontombi Marylucy Mbelle, Mohamed Said

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

John Osei SekyereDepartment of Medical Microbiology, School of Medicine, University of Pretoria, Pretoria, South Africa.
Masego MmatliDepartment of Medical Microbiology, School of Medicine, University of Pretoria, Pretoria, South Africa.
Anel BoschDepartment of Medical Microbiology, School of Medicine, University of Pretoria, Pretoria, South Africa.
Ramathetje Virginia NtsoaneDepartment of Medical Microbiology, School of Medicine, University of Pretoria, Pretoria, South Africa.
Harishia NaidooDepartment of Medical Microbiology, School of Medicine, University of Pretoria, Pretoria, South Africa.
Sinenhlanhla DoyisaDepartment of Microbiology, School of Life Sciences, University of KwaZulu-Natal, Durban, South Africa.
Nontuthuko E ManingiDepartment of Microbiology, School of Life Sciences, University of KwaZulu-Natal, Durban, South Africa.
Nontombi Marylucy MbelleDepartment of Medical Microbiology, School of Medicine, University of Pretoria, Pretoria, South Africa.
Mohamed SaidDepartment of Medical Microbiology, School of Medicine, University of Pretoria, Pretoria, South Africa.
University of Pretoria · ZAUniversity of KwaZulu-Natal · ZANational Health Laboratory Service · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: An outbreak of multidrug-resistant Methods: Bacterial cultures obtained from clinical samples collected from the infected neonates underwent phenotypic and molecular analyses to determine their species, sensitivity to antibiotics, production of carbapenemases, complete resistance genes profile, clonality, epidemiology, and evolutionary relationships. Mobile genetic elements flanking the resistance genes and facilitating their spread were also characterized. Results: The outbreak was centered in two major wards and affected mainly neonates between September 2019 and March 2020. Most isolates (n = 27 isolates) were Conclusions: The outbreak of fatal MDR infections in the neonatal wards were mediated by clonal (vertical) and horizontal (plasmid-mediated) spread of resistant and virulent strains (and genes) that have been also circulating locally and globally.

Indexed as

Enterobacteriaceae InfectionsKlebsiella pneumoniaeAnti-Bacterial Agentsbeta-LactamasesDisease OutbreaksEnterobacter cloacaeEscherichia coliHumansInfant, NewbornMicrobial Sensitivity TestsMolecular EpidemiologySouth AfricaTertiary Care CentersAnti-Bacterial Agentsbeta-Lactamasescarbapenemcolistindrug resistanceinfection controlneonatesoutbreakPretoriasepsis

Identifiers

PMID38481664
PMCPMC10933102
OpenAlexW4392235383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.