ArticleBMC cardiovascular disorders2024
Predictive value of the serum uric acid to high-density lipoprotein cholesterol ratio for culprit plaques in patients with acute coronary syndrome.
Article in BMC cardiovascular disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 33 citations in OpenAlex.
- Uric Acid-to-Magnesium Ratio as a Novel Biomarker of Angiographic Coronary Artery Disease Burden: A Retrospective Cross-Sectional Comparative Analysis with the Uric Acid-to-HDL Ratio and Frontal QRS-T Angle in Patients Undergoing Elective Coronary Angiography.Journal of cardiovascular development and disease · 2026Article
- Serum uric acid to HDL-cholesterol ratio predicts all-cause mortality in cancer patients based on NHANES data.Medicine · 2026Article
- A Novel Risk Score Based on Lipid-Related Biomarkers for Acute Coronary Syndromes: A Multicenter Machine Learning Study.Reviews in cardiovascular medicine · 2026Article
- Decoding the Uric Acid to HDL Cholesterol Ratio (UHR) as a Novel Metabolic Biomarker for Chronic Pain: Insights Into Precision Diagnostics and Management.Pain research & management · 2026Article
- Relationship of admission uric acid to high density lipoprotein cholesterol ratio with unfavorable prognosis among acute ischemic stroke patients.Lipids in health and disease · 2025Article
- Article
- The uric acid to high density lipoprotein cholesterol ratio as a new indicator for predicting coronary slow flow phenomenon.BMC cardiovascular disorders · 2025Article
- The association between serum uric acid to high-density lipoprotein cholesterol ratio and heart failure: a cross‑sectional study.BMC cardiovascular disorders · 2025Article
- Association of serum uric acid-to-high-density lipoprotein cholesterol ratio (UHR) with risk of myocardial infarction among individuals with diabetes: a cross-sectional analysis using data from NHANES 2005-2020.European journal of medical research · 2025Article
- Long-term cardiovascular risk and mortality associated with uric acid to HDL-C ratio: a 20-year cohort study in adults over 40.Scientific reports · 2025Article
- Elevated log uric acid-to-high-density lipoprotein cholesterol ratio (UHR) as a predictor of increased female infertility risk: insights from the NHANES 2013-2020.Lipids in health and disease · 2025Article
- Association between uric acid/high-density lipoprotein cholesterol ratio and testosterone deficiency in adult American men: findings from the national health and nutrition examination survey 2011-2016.BMC public health · 2025Article
- Association between serum uric acid to high-density lipoprotein cholesterol ratio (UHR) and abdominal aortic calcification: a cross-sectional study based on NHANES 2013-2014.Frontiers in cardiovascular medicine · 2025Article
- Article
- Article
- Increased uric acid to high-density lipoprotein ratio positively correlated with stroke risk.Frontiers in neurology · 2025Article
- A Cross-Sectional Study of the Association Between Uric Acid-to-High-Density Lipoprotein Cholesterol Ratio and Carotid Atherosclerosis in Patients with Type 2 Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- The correlation between the uric acid to high-density lipoprotein cholesterol ratio and stroke.Frontiers in medicine · 2025Article
- Association Between Uric Acid to High-Density Lipoprotein Cholesterol Ratio and Kidney Function in Patients With Primary Aldosteronism: A Cross-Sectional Study.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- U-shaped association of uric acid to HDL cholesterol ratio (UHR) with ALL-cause and cardiovascular mortality in diabetic patients: NHANES 1999-2018.BMC cardiovascular disorders · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
backgroundHyperuricemia and low level of high-density lipoprotein cholesterol (HDL-C) are both risk factors for coronary artery disease (CAD). The uric acid to HDL-C ratio (UHR) has recently been identified as a new inflammatory and metabolic biomarker. However, the relationship between the UHR and coronary culprit plaques has not been fully investigated in patients with acute coronary syndrome (ACS).
methodsA total of 346 patients with ACS were enrolled in this study. Culprit lesion characteristics were assessed by optical coherence tomography (OCT). Logistic regression and linear correlation analyses were performed to assess the association between the UHR and culprit plaques. The predictive value of the UHR was investigated by receiver operating characteristic (ROC) curve analysis.
resultsThe percentages of typical culprit plaques, including ruptures, erosions and thrombi, were greater in the high-UHR subgroup than those in the low-UHR subgroup. A positive relationship was also found between the UHR and diameter stenosis (r = 0.160, P = 0.003) and between the UHR and area stenosis (r = 0.145, P = 0.007). The UHR was found to be independently associated with plaque rupture, erosion and thrombus. Furthermore, ROC analysis suggested that the UHR had a better predictive value than low-density lipoprotein cholesterol.
conclusionsAn elevated UHR level was independently related to the occurrence rate of culprit plaques. The UHR is a simple and easily acquired parameter for detecting culprit plaques in patients with ACS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.