Evidence map›Paper›PMID 38480885›Full record

ArticleNature2024

Substrate-induced condensation activates plant TIR domain proteins.

Wen Song, Li Liu, Dongli Yu, Hanna Bernardy, Jan Jirschitzka, Shijia Huang, Aolin Jia, Wictoria Jemielniak, Julia Acker, Henriette Laessle and 8 more

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
31.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Mechanisms and balanced regulation of plant immunity.Nature reviews. Molecular cell biology · 2026
    Review
  4. Article
  5. Review
  6. High‑density mapping of stripe rust resistance gene YrH8 in wheat line Hangmai 8.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Plant NLRs are getting into higher-order architectures.The Plant journal : for cell and molecular biology · 2026
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Molecular mechanisms of plant NLR activation and signalling.The Plant journal : for cell and molecular biology · 2026
    Review
  16. PAR-Driven Condensation Maintains Stalled Replication Fork Stability.bioRxiv : the preprint server for biology · 2026
    Article
  17. TIR innovations in plant immunity.The New phytologist · 2026
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 3 countries.

Wen Song *State Key Laboratory of Plant Environmental Resilience, College of Biological Sciences, China Agricultural University, Beijing, China.ORCID 0000-0002-9498-2409
Li Liu *Department of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne, Germany.
Dongli YuDepartment of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne, Germany.
Hanna BernardyInstitute of Biochemistry, University of Cologne, Cologne, Germany.ORCID 0009-0003-7536-954X
Jan JirschitzkaInstitute of Biochemistry, University of Cologne, Cologne, Germany.
Shijia HuangSchool of Life Sciences, Westlake University, Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, Zhejiang, China.
Aolin JiaTsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, School of Life Sciences, Tsinghua University, Beijing, China.
Wictoria JemielniakInstitute of Biochemistry, University of Cologne, Cologne, Germany.
Julia AckerInstitute of Biochemistry, University of Cologne, Cologne, Germany.ORCID 0000-0002-6422-6514
Henriette LaessleDepartment of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne, Germany.ORCID 0000-0002-1940-3745
Junli WangDepartment of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne, Germany.ORCID 0000-0001-8825-3894
Qiaochu ShenDepartment of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne, Germany.
Weijie ChenTsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, School of Life Sciences, Tsinghua University, Beijing, China.
Pilong LiTsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, School of Life Sciences, Tsinghua University, Beijing, China.ORCID 0000-0002-1783-3100
Jane E ParkerDepartment of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne, Germany.ORCID 0000-0002-4700-6480
Zhifu HanSchool of Life Sciences, Westlake University, Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, Zhejiang, China.ORCID 0000-0002-2608-9088
Paul Schulze-LefertDepartment of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne, Germany. schlef@mpipz.mpg.de.ORCID 0000-0002-8978-1717
Jijie ChaiDepartment of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne, Germany. chaijijie@westlake.edu.cn.ORCID 0000-0001-7591-3873
University of Cologne · DEMax Planck Institute for Plant Breeding Research · DECenter for Life Sciences · CNWestlake University · CNBeijing Normal University · CNCluster of Excellence on Plant Sciences · DEHoward Hughes Medical Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant nucleotide-binding leucine-rich repeat (NLR) immune receptors with an N-terminal Toll/interleukin-1 receptor (TIR) domain mediate recognition of strain-specific pathogen effectors, typically via their C-terminal ligand-sensing domains

Indexed as

Adenosine TriphosphateArabidopsisNADNicotianaPhase SeparationPlant ProteinsProtein DomainsArabidopsis ProteinsCell DeathMutationNLR ProteinsPlant DiseasesPlant ImmunityPromoter Regions, GeneticReceptors, ImmunologicReceptors, Interleukin-1Adenosine TriphosphateArabidopsis ProteinsNADNLR ProteinsPlant ProteinsReceptors, ImmunologicReceptors, Interleukin-1Toll-Like Receptors

Identifiers

PMID38480885
PMCPMC10972746
OpenAlexW4392747600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.