Evidence map›Paper›PMID 38480600›Full record

ReviewMetabolomics : Official journal of the Metabolomic Society2024

Perspective: use and reuse of NMR-based metabolomics data: what works and what remains challenging.

Goncalo Jorge Gouveia, Thomas Head, Leo L Cheng, Chaevien S Clendinen, John R Cort, Xiuxia Du, Arthur S Edison, Candace C Fleischer, Jeffrey Hoch, Nathaniel Mercaldo and 8 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Metabolomics : Official journal of the Metabolomic Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Parsing Neurometabolic Signatures of Multiple Sclerosis with MRSI and cPCA.medRxiv : the preprint server for health sciences · 2026
    Article
  2. Review
  3. Article
  4. A Reproducibility Crisis for Clinical Metabolomics Studies.Trends in analytical chemistry : TRAC · 2024
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Goncalo Jorge GouveiaMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada.ORCID 0000-0002-3022-7332
Thomas HeadMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada.ORCID 0009-0001-3765-7343
Leo L ChengMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada.ORCID 0000-0001-5975-5406
Chaevien S ClendinenMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada.
John R CortMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada.ORCID 0000-0001-6342-6461
Xiuxia DuMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada.ORCID 0000-0002-3468-9585
Arthur S EdisonMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada.ORCID 0000-0002-5686-2350
Candace C FleischerMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada.ORCID 0000-0003-3265-2276
Jeffrey HochMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada.ORCID 0000-0002-9230-2019
Nathaniel MercaldoMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada.ORCID 0000-0003-1658-6598
Wimal PathmasiriMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada.ORCID 0000-0002-5199-5744
Daniel RafteryMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada.ORCID 0000-0003-2467-8118
Tracey B SchockMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada.ORCID 0000-0002-1808-7816
Lloyd W SumnerMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada.ORCID 0000-0002-4086-663X
Panteleimon G TakisMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada.ORCID 0000-0002-7224-0412
Valérie CopiéMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada.ORCID 0000-0002-2778-1463
Hamid R EghbalniaMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada.ORCID 0000-0002-5073-1819
Robert PowersMetabolomics Association of North America (MANA), NMR Special Interest Group, Edmonton, Canada. rpowers3@unl.edu.ORCID 0000-0001-9948-6837

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe National Cancer Institute issued a Request for Information (RFI; NOT-CA-23-007) in October 2022, soliciting input on using and reusing metabolomics data. This RFI aimed to gather input on best practices for metabolomics data storage, management, and use/reuse. AIM OF REVIEW: The nuclear magnetic resonance (NMR) Interest Group within the Metabolomics Association of North America (MANA) prepared a set of recommendations regarding the deposition, archiving, use, and reuse of NMR-based and, to a lesser extent, mass spectrometry (MS)-based metabolomics datasets. These recommendations were built on the collective experiences of metabolomics researchers within MANA who are generating, handling, and analyzing diverse metabolomics datasets spanning experimental (sample handling and preparation, NMR/MS metabolomics data acquisition, processing, and spectral analyses) to computational (automation of spectral processing, univariate and multivariate statistical analysis, metabolite prediction and identification, multi-omics data integration, etc.) studies. KEY SCIENTIFIC CONCEPTS OF REVIEW: We provide a synopsis of our collective view regarding the use and reuse of metabolomics data and articulate several recommendations regarding best practices, which are aimed at encouraging researchers to strengthen efforts toward maximizing the utility of metabolomics data, multi-omics data integration, and enhancing the overall scientific impact of metabolomics studies.

Indexed as

Magnetic Resonance ImagingMetabolomicsAutomationMagnetic Resonance SpectroscopyMass SpectrometryBest practicesMass spectrometryMetabolomicsNMRUse and reuse of metabolomics datasets

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.