Evidence map›Paper›PMID 38480465›Full record

ReviewExpert review of cardiovascular therapy

Why selective screening for asymptomatic carotid stenosis is currently appropriate: a special report.

Kosmas I Paraskevas, Alan Dardik, Marc L Schermerhorn, Christos D Liapis, Armando Mansilha, Brajesh K Lal, William A Gray, Martin M Brown, Piotr Myrcha, Carl J Lavie and 13 more

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Expert review of cardiovascular therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Hemodynamics in carotid artery stenosis.International angiology : a journal of the International Union of Angiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 20 institutions in 9 countries.

Kosmas I ParaskevasDepartment of Vascular Surgery, Red Cross Hospital, Athens, Greece.
Alan DardikDepartment of Surgery, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0001-5022-7367
Marc L SchermerhornDepartment of Surgery, Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Christos D LiapisDepartment of Vascular Surgery, Athens Vascular Research Center, Athens, Greece.
Armando MansilhaFaculty of Medicine of the University of Porto, Porto, Portugal.
Brajesh K LalDepartment of Vascular Surgery, University of Maryland School of Medicine, Baltimore, USA.
William A GrayLankenau Heart Institute, Wynnewood, PA, USA.
Martin M BrownStroke Research Centre, UCL Institute of Neurology, University College London, London, UK.
Piotr MyrchaDepartment of General and Vascular Surgery, Faculty of Medicine, Medical University of Warsaw, Warsaw, Poland.
Carl J LavieJohn Ochsner Heart and Vascular Institute, Ochsner Clinical School, The University of Queensland School of Medicine, New Orleans, LA, USA.
Clark J ZeebregtsDepartment of Surgery (Division of Vascular Surgery), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Eric A SecemskySmith Center for Outcomes Research, Division of Cardiology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Luca SabaDepartment of Radiology, Azienda Ospedaliera Universitaria Di Cagliari, Cagliari, Italy.ORCID 0000-0003-2870-3771
Matthew BlechaDivision of Vascular Surgery, Stritch School of Medicine, Loyola University Chicago, Chicago, IL, USA.
Victor GurevichCenter of Atherosclerosis and Lipid Disorders, Lab of Microangiopathic Mechanisms of Atherogenesis, Saint-Petersburg State University, Mechnikov, Saint-Petersburgh, Russia.
Mauro SilvestriniNeurological Clinic, Department of Experimental and Clinical Medicine, Marche Polytechnic University, Ancona, Italy.
Ales BlincDepartment of Vascular Diseases, Division of Internal Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Alexei SvetlikovDivision of Vascular & Endovascular Surgery, North-Western Scientific Clinical Center of Federal Medical Biological Agency, Department of Hospital Surgery, Saint-Petersburg State University, Saint-Petersburg, Russia.
Jose Fernandes E FernandesCardiovascular Center (CCUL), Faculty of Medicine University of Lisbon, Lisbon, Portugal.
Peter A SchneiderDivision of Vascular and Endovascular Surgery, University of California, San Francisco, CA, USA.
Peter GloviczkiDivision of Vascular and Endovascular Surgery, Mayo Clinic, Rochester, MN, USA.
Christopher J WhiteJohn Ochsner Heart and Vascular Institute, Ochsner Clinical School, The University of Queensland School of Medicine, New Orleans, LA, USA.
Ali F AbuRahmaDepartment of Surgery, Division of Vascular and Endovascular Surgery, Charleston Area Medical Center/West Virginia University Health Sciences Center, Charleston, WV, USA.
Beth Israel Deaconess Medical Center · USOchsner Medical Center · USSt Petersburg University · RUAthens Medical Center · GRAzienda Ospedaliero-Universitaria Cagliari · ITLankenau Heart Institute · USLoyola University Chicago · USMarche Polytechnic University · ITMayo Clinic in Arizona · USMedical University of Warsaw · PLRed Cross Hospital · GRUniversidade do Porto · PTUniversity College London · GBUniversity Medical Center Groningen · NLUniversity of California, San Francisco · USUniversity of Lisbon · PTUniversity of Ljubljana · SIUniversity of Maryland, Baltimore · USWest Virginia University · USYale University · US

Funding

CREST-2 Clinical Coordinating CenterU01NS080168 · NINDS · MAYO CLINIC JACKSONVILLE · PI Thomas G Brott, JAMES F MESCHIA · 2014 to 2026
$56.3M
Shared Decision-Making to Improve the Health Status of Patients with Claudication: Developing and Implementing Strategies to Individualize Treatment DecisionsK23HL150290 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SECEMSKY, ERIC ALEXANDER · 2020 to 2024
$851k
CSRD VA I01 CX001621NHLBI NIH HHS K23 HL150290NINDS NIH HHS U01 NS080168
6 · The paper itself

Abstract

introductionTwo of the main reasons recent guidelines do not recommend routine population-wide screening programs for asymptomatic carotid artery stenosis (AsxCS) is that screening could lead to an increase of carotid revascularization procedures and that such mass screening programs may not be cost-effective. Nevertheless, selective screening for AsxCS could have several benefits. This article presents the rationale for such a program. AREAS COVERED: The benefits of selective screening for AsxCS include early recognition of AsxCS allowing timely initiation of preventive measures to reduce future myocardial infarction (MI), stroke, cardiac death and cardiovascular (CV) event rates. EXPERT OPINION: Mass screening programs for AsxCS are neither clinically effective nor cost-effective. Nevertheless, targeted screening of populations at high risk for AsxCS provides an opportunity to identify these individuals earlier rather than later and to initiate a number of lifestyle measures, risk factor modifications, and intensive medical therapy in order to prevent future strokes and CV events. For patients at 'higher risk of stroke' on best medical treatment, a prophylactic carotid intervention may be considered.

Indexed as

Carotid StenosisCost-Benefit AnalysisMass ScreeningStrokeAsymptomatic DiseasesCardiovascular DiseasesHumansLife StyleMyocardial InfarctionPractice Guidelines as TopicRisk FactorsAsymptomatic carotid atherosclerosiscarotid plaque burdencarotid stenosisguidelinesscreeningstroke

Identifiers

PMID38480465
PMCPMC12746223
OpenAlexW4392814932

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.