ArticleBMJ open2024
Adverse birth outcomes and childhood overweight at age of 3-8 years in a prospective cohort study in Tianjin, China.
Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 4 citations in OpenAlex.
- Birthweight and cardiometabolic risk factors in offspring: A systematic review and meta-analysis of cohort studies.Archives of public health = Archives belges de sante publique · 2026Article
- The use of routine data sources to identify risk factors for overweight and obesity at 6 years of age. An Italian study in 8621 children born in 2010-2011-2012.Italian journal of pediatrics · 2025Observational
- Early Life Determinants of Overweight and Obesity in a Sample of Mexico City Preschoolers.Nutrients · 2025Article
- Visceral and subcutaneous adipose tissue in children born after ART with frozen and fresh embryo transfers.Human reproduction open · 2025Article
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Authors and funding
12 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo explore associations between adverse birth outcomes and childhood overweight at 3-8 years of age.
designA prospective cohort study.
settingSix central urban districts of Tianjin, China.
participants1681 woman-child pairs.
methods1681 woman-child pairs were followed up for 8 years in Tianjin, China. Demographic and clinical information including birth outcomes was collected longitudinally, commencing from first antenatal care visit till postpartum period. Offspring height and weight were measured at 3-8 years of age. High and low weight/length ratios (WLR) at birth were, respectively, defined as ≥90th and ≤10th gestational week and sex-specific percentiles. Overweight for children at 3-5 and 6-8 years of age were, respectively, defined as body mass index (BMI)-for-age and -sex above the 2 z-score and 1 z-score curves of the WHO's child growth standards. Binary logistic regression analysis was used to obtain ORs and 95% CI with a stepwise backward selection method to select independent predictors. PRIMARY OUTCOMES MEASURES: Childhood overweight.
resultsOf 1681 children, 10.7% (n=179) and 27.8% (n=468) developed overweight at 3-5 and 6-8 years of age, respectively. Large for gestational age (LGA) was associated with increased risk of overweight at 3-5 years of age (aOR: 1.86, 95% CI: 1.27 to 2.72) while high WLR at birth was associated with increased risk of overweight at 6-8 years of age (1.82, 1.41 to 2.34). Low WLR at birth was associated with decreased risk of overweight at 6-8 years of age (0.52, 0.30 to 0.90).
conclusionsLGA and high WLR at birth predicted childhood overweight at 3-5 and 6-8 years of age, respectively. Low WLR at birth was associated with decreased risk of childhood overweight at 6-8 years of age.
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