Evidence map›Paper›PMID 38479194›Full record

ArticlePsychiatry research2024

Associations of history of alcohol use disorder with loneliness, social support, and mental health during the COVID-19 pandemic.

Jeremy W Luk, Noa Leiter, Bethany L Stangl, Tommy Gunawan, Melanie L Schwandt, David Goldman, Nancy Diazgranados, Vijay A Ramchandani

Open access · greenAbstract read
In one paragraph

Article in Psychiatry research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
10.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Classification of Alcohol Use Disorder With Explainable AI.Alcohol, clinical & experimental research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jeremy W LukOffice of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States. Electronic address: jeremy.luk@nih.gov.
Noa LeiterHuman Psychopharmacology Laboratory, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States.
Bethany L StanglHuman Psychopharmacology Laboratory, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States.
Tommy GunawanOffice of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States; Human Psychopharmacology Laboratory, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States.
Melanie L SchwandtOffice of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States.
David GoldmanOffice of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States; Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, Rockville, MD, United States.
Nancy DiazgranadosOffice of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States.
Vijay A RamchandaniHuman Psychopharmacology Laboratory, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States.
National Institute on Alcohol Abuse and Alcoholism · US

Funding

NIAAA Repository/Screening Database Management and ResearchZIAAA000130 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI SCHWANDT, MELANIE · 2017 to 2025
$60.1M
Alcohol Pharmacokinetics and Pharmacodynamics in HumansZIAAA000466 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI RAMCHANDANI, VIJAY ARJUN · 2009 to 2025
$31.2M
Intramural NIH HHS ZIA AA000130Intramural NIH HHS ZIA AA000466
6 · The paper itself

Abstract

This study examined the effects of alcohol use disorder (AUD) and treatment history on changes in loneliness, social support, and mental health symptoms from before to during the pandemic, and tested loneliness and social support as mediators of the AUD-mental health associations. Participants (n = 427) enrolled in the NIAAA COVID-19 Pandemic Impact on Alcohol Study were categorized into three groups: healthy control (62.3%), nontreatment AUD (14.1%), and treatment AUD (23.7%). Multilevel generalized linear models were conducted to examine changes in loneliness, social support, and mental health symptoms by group. Path analyses tested the mediating roles of loneliness and social support. Loneliness increased during the pandemic, especially in the nontreatment AUD group. Social support decreased in the healthy control and AUD treatment group. Anxiety and depressive symptoms increased in the nontreatment AUD group. Individuals with a history of AUD regardless of treatment history reported greater loneliness, which was linked to higher anxiety and depressive symptoms. Loneliness, but not social support, mediated the AUD-mental health associations. Psychosocial interventions aimed at increasing positive social engagement among individuals with AUD may help alleviate feelings of loneliness and mitigate mental health symptoms. Study findings can also help improve preparedness for future public health crises.

Indexed as

AlcoholismCOVID-19AnxietyDepressionHumansLonelinessMental HealthPandemicsSocial SupportAlcohol use disorderCOVID-19LonelinessMental healthSocial support

Identifiers

PMID38479194
PMCPMC11229409
OpenAlexW4392204028

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.