Evidence map›Paper›PMID 38478744›Full record

ArticleAging2024

Novel histone acetylation-related lncRNA signature for predicting prognosis and tumor microenvironment in esophageal carcinoma.

Batter Han, Ying Ma, Pengjie Yang, Fangchao Zhao, Haiyong Zhu, Shujun Li, Rong Yu, Subudao Bao

Abstract read
In one paragraph

Article in Aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Batter HanDepartment of Thoracic Surgery, Peking University Cancer Hospital Inner Mongolia Hospital, Hohhot 010010, China.
Ying MaDepartment of Thoracic Surgery, Mongolia Medical University Affiliated Hospital, Hohhot 010050, China.
Pengjie YangDepartment of Thoracic Surgery, Peking University Cancer Hospital Inner Mongolia Hospital, Hohhot 010010, China.
Fangchao ZhaoDepartment of Thoracic Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Haiyong ZhuDepartment of Thoracic Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Shujun LiDepartment of Thoracic Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Rong YuDepartment of Thoracic Surgery, Peking University Cancer Hospital Inner Mongolia Hospital, Hohhot 010010, China.
Subudao BaoMongolian Medicine College, Inner Mongolia Medical University, Hohhot 010110, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Histone acetylation is one of the most common epigenetic modifications and plays a crucial role in tumorigenesis. However, the prognostic significance of histone acetylation-related lncRNAs (HARlncRNAs) in esophageal carcinoma (ESCA) is not well understood. A total of 653 differentially expressed lncRNAs (DElncRNAs) were identified between 162 ESCA tissues and 11 normal tissues in the TCGA database, and 7 of them were correlated with acetylation regulators. We employed univariate Cox regression analysis, combining it with clinical prognosis information, to select 3 prognostic-related HARlncRNAs for further analysis. Subsequently, we used LASSO regression analysis to construct a risk signature for ESCA and identified

Indexed as

CarcinomaEsophageal NeoplasmsRNA, Long NoncodingAcetylationHistonesHumansPrognosisTumor MicroenvironmentHistonesRNA, Long Noncodingesophageal carcinomahistone acetylationimmunotherapytumor microenvironment

Identifiers

PMID38478744
PMCPMC11006502

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.