Evidence map›Paper›PMID 38478731›Full record

SynthesisThe Journal of infectious diseases2024

Systematic Review of Household Transmission of Strep A: A Potential Site for Prevention That Has Eluded Attention.

Stephanie L Enkel, Samuel Barnes, Jessica Daw, Emma Pearson, Hannah M M Thomas, Nina Lansbury, Rosemary Wyber, Andrew M Redmond, Anna P Ralph, Jonathan R Carapetis and 1 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The Journal of infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Stephanie L EnkelWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Australia.ORCID 0000-0003-4075-0781
Samuel BarnesSchool of Public Health, University of Queensland, Brisbane, Australia.
Jessica DawWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Australia.
Emma PearsonWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Australia.
Hannah M M ThomasWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Australia.
Nina LansburySchool of Public Health, University of Queensland, Brisbane, Australia.
Rosemary WyberWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Australia.
Andrew M RedmondSchool of Public Health, University of Queensland, Brisbane, Australia.
Anna P RalphDepartment of Infectious Diseases, Royal Darwin Hospital, Darwin, Australia.
Jonathan R CarapetisWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Australia.ORCID 0000-0002-1182-9792
Asha C BowenWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, Australia.ORCID 0000-0002-3242-1155

Funding

an NHMRC SynergyNHMRC GNT1173874University of QueenslandUniversity of Western Australia
6 · The paper itself

Abstract

backgroundAlthough Streptococcus pyogenes (Strep A) is the sixth-most common infectious disease globally, its transmission within the household remains an understudied driver of infection. We undertook a systematic review to better understand the transmission of Strep A among people within the home, while highlighting opportunities for prevention.

methodsA search strategy was applied to 5 databases between September 2022 and March 2023. Results were limited to articles published between January 2000 and March 2023. Texts were reviewed by 2 authors and the following data extracted: article details (title, author, year), study type, transmission year, country, participant age, infection status, molecular testing, and transmission mode. Funding was provided by the Australian National Health and Medical Research Council (GNT2010716).

resultsThe final analysis comprised 28 texts. Only 7 studies (25.0%) provided sufficient detail to identify the Strep A transmission mode: contact (n = 4), vehicle (bedding, clothing, other fabric, and medical equipment; n = 2), and contact with animals (n = 1). All others were classified as household (specific mode unascertainable). Most articles reported outbreaks involving invasive Strep A infections.

conclusionsThere is limited literature regarding household transmission of Strep A. Understanding transmission in this setting remains imperative to guide control methods.

Indexed as

Family CharacteristicsStreptococcal InfectionsStreptococcus pyogenesAnimalsAustraliaDisease OutbreaksHumanshouseholdsinfectious diseaseStreptococcus pyogenessystematic reviewtransmission

Identifiers

PMID38478731
PMCPMC11481456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.