Evidence map›Paper›PMID 38478315›Full record

ArticleBiological trace element research2024

Therapeutic Potential of Aloe vera and Aloe vera-Conjugated Silver Nanoparticles on Mice Exposed to Hexavalent Chromium.

Tooba Nauroze, Shaukat Ali, Shagufta Andleeb, Chaman Ara, Iqra Liaqat, Hina Mushtaq, Samaira Mumtaz, Lubna Kanwal, Afshan Syed Abbas, Shumaila Mumtaz and 2 more

RetractedAbstract readRetracted Publication
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Mechanism of Liver Injury Induced by CrAnimals : an open access journal from MDPI · 2026
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Tooba NaurozeApplied Entomology and Medical Toxicology Laboratory, Department of Zoology, Government College University, Lahore, Pakistan.
Shaukat AliApplied Entomology and Medical Toxicology Laboratory, Department of Zoology, Government College University, Lahore, Pakistan. dr.shaukatali@gcu.edu.pk.
Shagufta AndleebDepartment of Zoology, University of Education, Lahore, Pakistan.
Chaman AraInstitute of Zoology, University of the Punjab, Lahore, Pakistan.
Iqra LiaqatApplied Entomology and Medical Toxicology Laboratory, Department of Zoology, Government College University, Lahore, Pakistan.
Hina MushtaqApplied Entomology and Medical Toxicology Laboratory, Department of Zoology, Government College University, Lahore, Pakistan.
Samaira MumtazApplied Entomology and Medical Toxicology Laboratory, Department of Zoology, Government College University, Lahore, Pakistan.
Lubna KanwalDepartment of Zoology, University of Okara, Lahore, Pakistan.
Afshan Syed AbbasDepartment of Zoology, University of Education, Lahore, Pakistan.
Shumaila MumtazApplied Entomology and Medical Toxicology Laboratory, Department of Zoology, Government College University, Lahore, Pakistan.
Muhammad Adeel FarooqApplied Entomology and Medical Toxicology Laboratory, Department of Zoology, Government College University, Lahore, Pakistan.
Istaqlal Hussain KhanDepartment of Zoology, Government College University, Faisalabad, Pakistan.
Government College University, Lahore · PKUniversity of Okara · PKUniversity of Azad Jammu and Kashmir · PKGovernment College University, Faisalabad · PKUniversity of the Punjab · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hexavalent chromium (Cr (VI)) is a hazardous heavy metal that induces hepatotoxicity and nephrotoxicity. Thus, this study was planned to explore the ameliorating capacity of Aloe vera leaf gel extract (AV) and their conjugated silver nanoparticles (AVNP) against Cr (VI) induced hepatotoxicity and renal toxicity. The organ indices, level of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, malondialdehyde, total protein, and creatinine in blood serum were measured. The histopathological and micrometric analysis of the hepatic and renal tissue sections were studied. The hepatosomatic index was raised significantly (0.098 ± 0.13 g) in Cr treated group. The blood serum level of AST (484 ± 10.7 U/L), ALT (163 ± 5.5 U/L), ALP (336.7 ± 9.5 U/L), MDA (642.3 ± 28.3 U/L), and creatinine (4.0 ± 0.1 mg/dL) were increased significantly, whereas total protein level was declined (2.8 ± 0.3 g/dL) significantly in Cr exposed group. In the histopathological study, necrosis, disturbed hepatic cords, impaired glomeruli, and Bowman's capsule were noted. Micrometric data from the liver and kidney revealed a significant surge in the size of hepatocytes and their nuclei (1188.2 ± 467.7 µ

Indexed as

AloeChromiumMetal NanoparticlesPlant ExtractsSilverAnimalsKidneyLiverMaleMiceOxidative StressPlant PreparationsAloe vera gelChromiumchromium hexavalent ionPlant ExtractsPlant PreparationsSilverHepatocytesHexavalent chromiumHistopathologyMicrometryNecrosis

Identifiers

PMID38478315
OpenAlexW4392749851

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.