ArticleSurgery today2024
Prolonged warm ischemia time in the recipient is associated with post-transplant biliary stricture following living-donor liver transplantation.
Article in Surgery today, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- The efficacy of intraoperative external biliary drainage tubes for late benign biliary strictures in hepaticojejunostomy after pancreaticoduodenectomy.Surgery today · 2026Article
- A graft-to-recipient weight ratio of less than 0.7% under portal venous hemodynamics monitoring is a risk factor for early graft loss after living donor liver transplantation.Surgery today · 2025Article
- Shortening the recipient warm ischemia time could be a strategy for expanding the liver donor pool.World journal of gastroenterology · 2025Article
- Recipient warm ischemic time negatively influences biliary complications and graft survival - a single center retrospective analysis.Frontiers in gastroenterology (Lausanne, Switzerland) · 2025Article
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
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Abstract
purposePost-transplant biliary stricture (PBS) is a common and important complication following orthotopic liver transplantation (LT). This study clarified the incidence of PBS and identified its risk factors.
methodsWe retrospectively reviewed the medical records of 67 patients who underwent living-donor LT (LDLT) at our institute between June 2010 and July 2022 and analyzed their clinical characteristics, prognosis, and risk factors for PBS.
resultsOf the 67 patients, 26 (38.8%) developed PBS during the observation period. Multivariate analyses revealed the following independent risk factors for PBS formation: increased red cell transfusion volume per body weight (> 0.2 U/kg; hazard ratio [HR], 3.8; P = 0.002), increased portal vein pressure (PVP) at the end of LT (> 16 mmHg; HR, 2.88; P = 0.032), postoperative biliary leakage (HR, 4.58; P = 0.014), and prolonged warm ischemia time (WIT) (> 48 min; HR, 4.53; P = 0.008). In patients with PBS, the cumulative incidence of becoming stent free was significantly higher in patients with a WIT ≤ 48 min than in those with a WIT > 48 min (P = 0.038).
conclusionProlonged WIT is associated with intractable PBS following LDLT.
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