ReviewInternational ophthalmology2024
Corneal biomechanics and diagnostics: a review.
Review in International ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Corneal biomechanical changes in patients with anterior chamber inflammation: a systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Pooled it
- Regional Dependence of Corvis ST Biomechanical Parameters on Corneal Material Properties: A Finite Element Study.Bioengineering (Basel, Switzerland) · 2026Article
- Evaluation of the effect of subepithelial infiltrates following adenoviral keratoconjunctivitis on corneal biomechanics: Corvis ST analysis.BMC ophthalmology · 2026Article
- Non-Contact IOP Estimation Based on Corneal Stress Birefringence: Experimental and Computational Validation.Sensors (Basel, Switzerland) · 2026Article
- Proteomic Analysis of Human Corneal Keratocytes Reveals Mechanical Strain-Dependent Changes in Cellular Function.Investigative ophthalmology & visual science · 2026Article
- Structure and Function of Ocular Proteoglycans: Essential Proteins for Vision.International journal of molecular sciences · 2026Review
- Quantitative assessment of the biomechanical properties of healthy human myopic corneas using Brillouin spectroscopy.BMC ophthalmology · 2026Article
- In Vivo Biomechanical Characteristics of Human Corneas With Phase-Decorrelation OCT.Investigative ophthalmology & visual science · 2026Article
- Corneal Biomechanics in Glaucoma: Current Evidence for Diagnosis, Risk Stratification, and Prognosis.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- Enhancing the diagnostic precision of subclinical keratoconus by combining indices from Scheimpflug tomography, corneal biomechanics, and anterior segment optical coherence tomography.International journal of ophthalmology · 2026Article
- Article
- Multifactorial analysis of corneal biomechanical stability after deep anterior lamellar keratoplasty: integration of anterior segment imaging indices and ocular response analyzer data.American journal of translational research · 2026Article
- Reactive oxygen species accelerated glycation for oxygen-independent corneal cross-linking.Frontiers in bioengineering and biotechnology · 2026Article
- Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration.Advanced healthcare materials · 2026Review
- Central corneal thickness, corneal endothelial cell density, and morphology in myopic eyes of young Chinese candidates for refractive surgery.Frontiers in ophthalmology · 2026Article
- Comparative corneal biomechanical changes after FS-LASIK and orthokeratology.Biomedical engineering online · 2025Article
- Exploring biomarkers for keratoconus: current insights and future directions.Molecular biology reports · 2025Review
- Nanoindentation under retrocorneal pressure to determine the biomechanical response of the human cornea to accelerated UVA crosslinking and riboflavin osmolarity ex vivo.Scientific reports · 2025Article
- The Impact of Dry Eye Disease on Corneal Biomechanics Analyzed with Corneal Visualization Scheimpflug Technology.Biomedicines · 2025Article
- Analysis of pulsatile motion in the murine cornea using phase-sensitive visible-light optical coherence tomography.Biomedical optics express · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
Abstract
purposeCorneal biomechanics is an emerging field and the interest into physical and biological interrelations in the anterior part of the eye has significantly increased during the past years. There are many factors that determine corneal biomechanics such as hormonal fluctuations, hydration and environmental factors. Other factors that can affect the corneas are the age, the intraocular pressure and the central corneal thickness. The purpose of this review is to evaluate the factors affecting corneal biomechanics and the recent advancements in non-destructive, in vivo measurement techniques for early detection and improved management of corneal diseases.
methodsUntil recently, corneal biomechanics could not be directly assessed in humans and were instead inferred from geometrical cornea analysis and ex vivo biomechanical testing. The current research has made strides in studying and creating non-destructive and contactless techniques to measure the biomechanical properties of the cornea in vivo.
resultsResearch has indicated that altered corneal biomechanics contribute to diseases such as keratoconus and glaucoma. The identification of pathological corneas through the new measurement techniques is imperative for preventing postoperative complications.
conclusionsIdentification of pathological corneas is crucial for the prevention of postoperative complications. Therefore, a better understanding of corneal biomechanics will lead to earlier diagnosis of ectatic disorders, improve current refractive surgeries and allow for a better postoperative treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.