Evidence map›Paper›PMID 38478090›Full record

ArticleWorld journal of urology2024

Transcutaneous tibial nerve stimulation in patients with multiple sclerosis and overactive bladder: a real-life clinical and urodynamic assessment.

Claire Hentzen, Camille Chesnel, Philippe Lagnau, Emilie Blouet, Maëlys Teng, Gérard Amarenco

Abstract read
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In one paragraph

Article in World journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Claire HentzenSorbonne University, GRC 01, GREEN Group of Clinical REsEarch in Neurourology, AP-HP, Hôpital Tenon, Service de Neuro-Urologie, 4 Rue de La Chine, 75020, Paris, France. claire.hentzen@aphp.fr.ORCID http://orcid.org/0000-0002-9223-4925
Camille ChesnelSorbonne University, GRC 01, GREEN Group of Clinical REsEarch in Neurourology, AP-HP, Hôpital Tenon, Service de Neuro-Urologie, 4 Rue de La Chine, 75020, Paris, France.
Philippe LagnauSorbonne University, GRC 01, GREEN Group of Clinical REsEarch in Neurourology, AP-HP, Hôpital Tenon, Service de Neuro-Urologie, 4 Rue de La Chine, 75020, Paris, France.
Emilie BlouetSorbonne University, GRC 01, GREEN Group of Clinical REsEarch in Neurourology, AP-HP, Hôpital Tenon, Service de Neuro-Urologie, 4 Rue de La Chine, 75020, Paris, France.
Maëlys TengSorbonne University, GRC 01, GREEN Group of Clinical REsEarch in Neurourology, AP-HP, Hôpital Tenon, Service de Neuro-Urologie, 4 Rue de La Chine, 75020, Paris, France.
Gérard AmarencoSorbonne University, GRC 01, GREEN Group of Clinical REsEarch in Neurourology, AP-HP, Hôpital Tenon, Service de Neuro-Urologie, 4 Rue de La Chine, 75020, Paris, France.
Sorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe aims of the present study were to assess the effectiveness of transcutaneous tibial nerve stimulation (TTNS) on overactive bladder (OAB) symptoms and on urodynamic parameters in patients with multiple sclerosis (PwMS) and to seek predictive factors of satisfaction.

methodsAll PwMS who performed 12-24 weeks of TTNS and who underwent urodynamic assessment before and after treatment between June 2020 and October 2022 were included retrospectively. Data collected were bladder diaries, symptoms assessed with Urinary Symptoms Profile (USP), and urodynamic parameters (bladder sensations, detrusor overactivity, and voiding phase). Patients with improvement rated as very good or good on Patient Global Impression of Improvement (PGI-I) score were considered as responders.

resultsEighty-two patients were included (mean age: 47.1 ± 11.5 years, 67 (82%) were women). The mean USP OAB sub-score decreased from 7.7 ± 3.5 to 6.0 ± 3.4 (p < 0.0001). On bladder diaries, voided volumes, void frequency, and the proportion of micturition done at urgent need to void significantly improved with TTNS (p < 0.05). No significant change was found in urodynamic parameters. According to the PGI-I, 34 (42.5%) patients were good responders. The only parameter associated with higher satisfaction was the percentage of micturition done at urgent need to void before the initiation of the treatment (39.8% ± 30.5 in the responder group vs 25.1% ± 25.6 in the low/no responder group; p = 0.04).

conclusionTTNS improves OAB symptoms in PwMS, without significant changes on urodynamics. A high rate of strong or urgent need to void in daily life was associated with higher satisfaction.

Indexed as

Multiple SclerosisTranscutaneous Electric Nerve StimulationUrinary Bladder, OveractiveAdultFemaleHumansMaleMiddle AgedRetrospective StudiesTibial NerveTreatment OutcomeUrodynamicsMultiple sclerosisTranscutaneous electric nerve stimulationUrinary bladder, overactiveUrodynamics

Identifiers

PMID38478090
OpenAlexW4392739884

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.