Evidence map›Paper›PMID 38478034›Full record

Observational studyAnnals of the Royal College of Surgeons of England2024

The effect of antiplatelet therapy and oral anticoagulants on the accuracy of faecal immunochemical testing.

F Wu, A A Khan, M Klimovskij, R Harshen

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Annals of the Royal College of Surgeons of England, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Are Colon Polyp Characteristics Really Different Between Men and Women?JGH open : an open access journal of gastroenterology and hepatology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

F WuEast Sussex Hospitals NHS Trust, UK.ORCID 0000-0002-8295-788X
A A KhanEast Kent Hospitals University NHS Trust, UK.
M KlimovskijEast Sussex Hospitals NHS Trust, UK.
R HarshenEast Sussex Hospitals NHS Trust, UK.
East Sussex Healthcare NHS Trust · GBEast Kent Hospitals University NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFaecal immunochemical testing (FIT) has been adopted to identify patients requiring further investigations on the colorectal cancer (CRC) referral pathway. We aimed to investigate the effect of antiplatelet and anticoagulant drugs on the accuracy of FIT results.

methodsThis observational study categorised patients with suspected CRC symptoms, who completed both FIT and colonic investigations, into two groups (control and exposed) based on their use of antiplatelet and anticoagulant drugs. Two-by-two tables and receiver operating characteristic (ROC) curve analysis were used to determine accuracy.

resultsA total of 928 patients were divided into a control (

conclusionsFIT accuracy for CRC detection remained unaffected despite more patients testing positive in the exposed group. FIT should be considered a supplementary tool for triage. Antiplatelet and anticoagulant drugs do not need to be discontinued before collection of FIT.

Indexed as

AnticoagulantsColorectal NeoplasmsOccult BloodPlatelet Aggregation InhibitorsAdministration, OralAgedAged, 80 and overEarly Detection of CancerFecesFemaleHumansMaleMiddle AgedPredictive Value of TestsROC CurveSensitivity and SpecificityAnticoagulantsPlatelet Aggregation InhibitorsAnticoagulationColorectal cancerScreening

Identifiers

PMID38478034
PMCPMC11214854
OpenAlexW4392740288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.