Evidence map›Paper›PMID 38477725›Full record

ArticleCadernos de saude publica2024

Psychoactive substance consumption after the Fundão dam mine tailing disaster in Minas Gerais State, Brazil.

Elaine Silva Miranda, Marcelo Dell'Aringa, Everaldo Alves da Costa, Thais Piazza, Francesco Della Corte, Luca Ragazzoni, Francesco Barone-Adesi, Carla Lourenço Tavares de Andrade, Claudia Garcia Serpa Osorio-de-Castro

Abstract read
In one paragraph

Article in Cadernos de saude publica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elaine Silva MirandaFaculdade de Farmácia, Universidade Federal Fluminense, Niterói, Brasil.ORCID 0000-0002-6204-5023
Marcelo Dell'AringaCenter for Research and Training in Disaster Medicine, Humanitarian Aid, and Global Health, Università del Piemonte Orientale, Novara, Italy.ORCID 0000-0002-4743-3263
Everaldo Alves da CostaBlissMe Tech, Rio de Janeiro, Brasil.ORCID 0000-0002-8118-8644
Thais PiazzaFaculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil.ORCID 0000-0001-9385-7609
Francesco Della CorteCenter for Research and Training in Disaster Medicine, Humanitarian Aid, and Global Health, Università del Piemonte Orientale, Novara, Italy.ORCID 0000-0003-1736-2318
Luca RagazzoniCenter for Research and Training in Disaster Medicine, Humanitarian Aid, and Global Health, Università del Piemonte Orientale, Novara, Italy.ORCID 0000-0002-2528-4375
Francesco Barone-AdesiCenter for Research and Training in Disaster Medicine, Humanitarian Aid, and Global Health, Università del Piemonte Orientale, Novara, Italy.ORCID 0000-0003-1550-436X
Carla Lourenço Tavares de AndradeEscola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.ORCID 0000-0003-3232-0917
Claudia Garcia Serpa Osorio-de-CastroEscola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.ORCID 0000-0003-4875-7216

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disasters cause changes in morbidity, mortality, and medicine use. Brazil is one of the main producers of mineral ores at great environmental cost. Mine tailings are stored in dams and ruptures have led to major disasters. We investigated the consumption of psychoactive medicines in the municipalities affected by the Fundão dam disaster in Minas Gerais State. An ecological study was carried out on drug consumption, estimated using public purchases in Minas Gerais and dispensing data from private retail pharmacies. Consumption (in number of defined daily doses/100,000 inhabitants per day) was analyzed descriptively in eight municipalities, stratified according to consumption level during a 25-month period. Six comparisons of mean consumption values for both data sets were done for pre- and post-disaster periods. The means of medicine consumption before and after the event were plotted and linear trends were added. Public purchase data evinced high consumption levels. Only pharmaceutical retail showed significant differences between the strata in the pre-disaster versus two post-disaster periods. Smaller municipalities showed an increase in consumption 15 months after the disaster. Clonazepam led the way in pharmaceutical retail consumption, followed by fluoxetine. Medicines showed an upward trend after the disaster. The high public provision may have stifled significant consumption patterns of psychoactive drugs; however, peak consumption were observed in private retail, suggesting a modification in use patterns after the disaster. The decrease in consumption immediately after the event was probably related to lower care-seeking behavior on the part of the population, and significant peaks after the disaster may reflect economic consequences of it.

Indexed as

DisastersMedicineBrazilFluoxetineHumansPharmaceutical PreparationsFluoxetinePharmaceutical Preparations

Identifiers

PMID38477725
PMCPMC10929881

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.