ArticleRadiology. Artificial intelligence2024
Assistive AI in Lung Cancer Screening: A Retrospective Multinational Study in the United States and Japan.
Open access · greenAbstract readMulticenter Study
In one paragraph
Article in Radiology. Artificial intelligence, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Diagnostic accuracy of deep learning-assisted low-dose CT screening for lung cancer detection: a systematic review and meta-analysis.Diagnostic and prognostic research · 2026Article
- Artificial intelligence-assisted early screening of lung cancer and accurate diagnosis of pulmonary nodules: research progress and clinical prospects from radiomics to multi-omics integration: a narrative review.Journal of thoracic disease · 2026Review
- Bridging the lung cancer screening eligibility gap: evaluation of guideline applicability in asymptomatic patients.Military Medical Research · 2026Observational
- Immunological and nutritional perspectives on macromolecular therapies for thoracic tumors.Frontiers in immunology · 2025Review
- Optimising artificial intelligence ultrasound tools in anaesthesiology and perioperative medicine: The next frontier for advanced technology application.Indian journal of anaesthesia · 2024Article
- Deep Learning-Based Joint Effusion Classification in Adult Knee Radiographs: A Multi-Center Prospective Study.Diagnostics (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors at 3 institutions in 2 countries.
Atilla P KiralyFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0000-0002-6613-3581
Corbin A CunninghamFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0000-0001-7864-3127
Ryan NajafiFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0000-0001-7055-2853
Zaid NabulsiFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0009-0001-2078-0142
Jie YangFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).
Charles LauFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0000-0002-3136-9711
Joseph R LedsamFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0000-0001-9917-7196
Wenxing YeFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).
Diego ArdilaFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).
Scott M McKinneyFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0000-0003-0707-7169
Rory PilgrimFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0009-0005-2582-8722
Yun LiuFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0000-0003-4079-8275
Hiroaki SaitoFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0000-0002-0824-454X
Yasuteru ShimamuraFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0000-0002-1096-1652
Mozziyar EtemadiFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0000-0002-6324-9220
David MelnickFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0000-0002-1535-697X
Sunny JansenFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).
Greg S CorradoFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0000-0001-8817-0992
Lily PengFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).
Daniel TseFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0000-0001-5315-8539
Shravya ShettyFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0000-0003-3783-3172
Shruthi PrabhakaraFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).
David P NaidichFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).
Neeral BeladiaFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0000-0001-9839-4076
Krish EswaranFrom Google Health Research, 1600 Amphitheatre Pkwy, Mountain View, CA 94043 (A.P.K., C.A.C., R.N., Z.N., C.L., J.R.L., D.A., S.M.M., R.P., Y.L., S.J., G.S.C., L.P., D.T., S.S., S.P., K.E.); Waymo, Mountain View, Calif (J.Y., N.B.), David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.L.); Google, Mountain View, Calif (W.Y.); Department of Gastroenterology, Sendai Kousei Hospital, Sendai, Japan (H.S.); MNES Inc, Hiroshima, Japan (Y.S.); Department of Telemedicine, Northwestern University Feinberg School of Medicine, Chicago, Ill (M.E., D.M.); and Center for Biological Imaging, New York University-Langone Medical Center, New York, NY (D.P.N.).ORCID 0000-0003-0241-5771
Google (United States) · USNorthwestern University · USNYU Langone Health · US
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose To evaluate the impact of an artificial intelligence (AI) assistant for lung cancer screening on multinational clinical workflows. Materials and Methods An AI assistant for lung cancer screening was evaluated on two retrospective randomized multireader multicase studies where 627 (141 cancer-positive cases) low-dose chest CT cases were each read twice (with and without AI assistance) by experienced thoracic radiologists (six U.S.-based or six Japan-based radiologists), resulting in a total of 7524 interpretations. Positive cases were defined as those within 2 years before a pathology-confirmed lung cancer diagnosis. Negative cases were defined as those without any subsequent cancer diagnosis for at least 2 years and were enriched for a spectrum of diverse nodules. The studies measured the readers' level of suspicion (on a 0-100 scale), country-specific screening system scoring categories, and management recommendations. Evaluation metrics included the area under the receiver operating characteristic curve (AUC) for level of suspicion and sensitivity and specificity of recall recommendations. Results With AI assistance, the radiologists' AUC increased by 0.023 (0.70 to 0.72;
Indexed as
Artificial IntelligenceEarly Detection of CancerLung NeoplasmsTomography, X-Ray ComputedAgedFemaleHumansJapanMaleMiddle AgedRadiographic Image Interpretation, Computer-AssistedRetrospective StudiesSensitivity and SpecificityUnited StatesAssistive Artificial IntelligenceCTLung Cancer Screening
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