Evidence map›Paper›PMID 38477559›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Mesenchymal Stem Cells-Involved Strategies for Rheumatoid Arthritis Therapy.

Chaoyang Li, Yifu Sun, Weiguo Xu, Fei Chang, Yinan Wang, Jianxun Ding

Open access · goldAbstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
18.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Lipopolysaccharide promotes rheumatoid arthritis by enhancing Wnt7b mediated macrophage-FLS communication.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Biocatalytic Nanoregulators Restore Joint Redox-Immune Homeostasis in Rheumatoid Arthritis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  14. Article
  15. Platelet-rich Plasma: ACurrent drug research reviews · 2026
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Chaoyang LiDepartment of Orthopedics, The Second Hospital of Jilin University, 4026 Yatai Street, Changchun, 130041, P. R. China.ORCID 0009-0009-6905-4473
Yifu SunDepartment of Orthopedics, The Second Hospital of Jilin University, 4026 Yatai Street, Changchun, 130041, P. R. China.ORCID 0000-0002-5347-3499
Weiguo XuKey Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, 130022, P. R. China.ORCID 0000-0002-0146-8532
Fei ChangDepartment of Orthopedics, The Second Hospital of Jilin University, 4026 Yatai Street, Changchun, 130041, P. R. China.ORCID 0000-0002-7141-5794
Yinan WangDepartment of Biobank, Division of Clinical Research, The First Hospital of Jilin University, 1 Xinmin Street, Changchun, 130061, P. R. China.ORCID 0000-0002-3352-9715
Jianxun DingKey Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, 130022, P. R. China.ORCID 0000-0002-5232-8863
Chinese Academy of Sciences · CNSecond Affiliated Hospital of Jilin University · CNJilin University · CN

Funding

Department of Finance of Jilin Province 2020SC2T001Innovative Research Group Project of the National Natural Science Foundation of China 52022095Innovative Research Group Project of the National Natural Science Foundation of China 52173149Innovative Research Group Project of the National Natural Science Foundation of China 52273158Innovative Research Group Project of the National Natural Science Foundation of China U23A20591Jilin Provincial Scientific and Technological Development Program 20190304121YYJilin Provincial Scientific and Technological Development Program 20210402006GHJilin Provincial Scientific and Technological Development Program 20210504001GHJilin Provincial Scientific and Technological Development Program 20210509005RQKey Technologies Research and Development Program 2021YFC2400600Key Technologies Research and Development Program 2022YFC2603500Key Technologies Research and Development Program 2022YFE0107700Natural Science Foundation of Hebei Province 52022095Youth Innovation Promotion Association of the Chinese Academy of Sciences 2019230Youth Science and Technology Talent Innovation Project of Changchun 21QC10
6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of the joints and bone destruction. Because of systemic administration and poor targeting, traditional anti-rheumatic drugs have unsatisfactory treatment efficacy and strong side effects, including myelosuppression, liver or kidney function damage, and malignant tumors. Consequently, mesenchymal stem cells (MSCs)-involved therapy is proposed for RA therapy as a benefit of their immunosuppressive and tissue-repairing effects. This review summarizes the progress of MSCs-involved RA therapy through suppressing inflammation and promoting tissue regeneration and predicts their potential clinical application.

Indexed as

Arthritis, RheumatoidMesenchymal Stem CellsMesenchymal Stem Cell TransplantationAnimalsHumansbiomaterialinflammation inhibitionmesenchymal stem cellrheumatoid arthritis therapytissue regeneration

Identifiers

PMID38477559
PMCPMC11200100
OpenAlexW4392741846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.