Evidence map›Paper›PMID 38477496›Full record

ArticleCancer medicine2024

Urban relatives ameliorate survival disparities for genitourinary cancer in rural patients.

Mouneeb Choudry, Kassandra Dindinger-Hill, Jacob Ambrose, Joshua Horns, Jeffrey Vehawn, Hailie Gill, Nicole Z Murray, Trevor C Hunt, Christopher Martin, Benjamin Haaland and 3 more

Erratum issuedAbstract read
In one paragraph

Article in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Mouneeb ChoudryHuntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
Kassandra Dindinger-HillHuntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0001-8322-6838
Jacob AmbroseHuntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
Joshua HornsHuntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
Jeffrey VehawnHuntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
Hailie GillHuntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
Nicole Z MurrayHuntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0001-8381-092X
Trevor C HuntHuntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0003-2439-7578
Christopher MartinHuntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
Benjamin HaalandHuntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
Jonathan ChipmanHuntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
Heidi A HansonDivision of Urology, University of Utah, Salt Lake City, Utah, USA.
Brock B O'NeilHuntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.

Funding

CTSA UM1 Program at University of UtahUM1TR004409 · NCATS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI RACHEL HESS, Jennifer Juhl Majersik · 2023 to 2026
$21.9M
Competition, Bundled Care Payment, and Low-Value Cancer CareK08CA234431 · NCI · UNIVERSITY OF UTAH · PI O'NEIL, BROCK · 2019 to 2023
$1.3M
NCATS NIH HHS UM1 TR004409NCI NIH HHS K08 CA234431NIH HHS
6 · The paper itself

Abstract

introductionPatients living in rural areas have worse cancer-specific outcomes. This study examines the effect of family-based social capital on genitourinary cancer survival. We hypothesized that rural patients with urban relatives have improved survival relative to rural patients without urban family.

methodsWe examined rural and urban based Utah individuals diagnosed with genitourinary cancers between 1968 and 2018. Familial networks were determined using the Utah Population Database. Patients and relatives were classified as rural or urban based on 2010 rural-urban commuting area codes. Overall survival was analyzed using Cox proportional hazards models.

resultsWe identified 24,746 patients with genitourinary cancer with a median follow-up of 8.72 years. Rural cancer patients without an urban relative had the worst outcomes with cancer-specific survival hazard ratios (HRs) at 5 and 10 years of 1.33 (95% CI 1.10-1.62) and 1.46 (95% CI 1.24-1.73), respectively relative to urban patients. Rural patients with urban first-degree relatives had improved survival with 5- and 10-year survival HRs of 1.21 (95% CI 1.06-1.40) and 1.16 (95% CI 1.03-1.31), respectively.

conclusionsOur findings suggest rural patients who have been diagnosed with a genitourinary cancer have improved survival when having relatives in urban centers relative to rural patients without urban relatives. Further research is needed to better understand the mechanisms through which having an urban family member contributes to improved cancer outcomes for rural patients. Better characterization of this affect may help inform policies to reduce urban-rural cancer disparities.

Indexed as

NeoplasmsUrogenital NeoplasmsHumansProportional Hazards ModelsRural PopulationUrban PopulationUtahfamilyrural healthurogenital neoplasms

Identifiers

PMID38477496
PMCPMC10935886

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