ArticleThe Journal of clinical endocrinology and metabolism2025
Effects of Overweight on Risk of Thyroid Nodules in Children and Adolescents: The Fukushima Health Management Survey.
Article in The Journal of clinical endocrinology and metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 2 citations in OpenAlex.
- Detection rate and maximum diameter of thyroid cysts among children and adolescents in thyroid ultrasound examination, The Fukushima Health Management Survey.Endocrine journal · 2026Article
- Effects of explanatory information on parental intentions regarding child participation in thyroid ultrasound examinations after the Fukushima nuclear power plant accident: a questionnaire survey.Endocrine journal · 2026Article
- Recent advances in the study of the correlation between obstructive sleep apnea and thyroid-disorders.Sleep & breathing = Schlaf & Atmung · 2025Review
- Potential implications of thyroid autoantibodies in children, adolescents, and young adults with thyroid nodules in Japan: The Fukushima Health Management Survey.Endocrine journal · 2024Article
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Authors and funding
17 authors at 2 institutions in 1 country.
Funding
Abstract
contextExamining how overweight/obesity impacts thyroid nodule development in children and adolescents by sex and age allows speculation on the mechanism.
objectiveWe examined whether overweight/obesity in children and adolescents is associated with thyroid nodule development by sex and age.
methodsApproximately 300 000 participants who underwent thyroid ultrasonography in the Fukushima Health Management Survey after a nuclear accident were enrolled. Those without nodules in the initial 2 examinations (1-3 and 4-5 years postaccident) were prospectively assessed for nodule development in the third examination (6-7 years postaccident) relative to baseline overweight status, with an average follow-up of 4.2 years. This was a population-based prospective cohort study. The first and second thyroid examinations involved 299 939 and 237 691 participants, respectively, excluding those with thyroid nodules. After the third examination, 184 519 participants were finalized for analysis. Multivariable adjusted odds ratios of new detected thyroid nodules for overweight participants were compared with normal-weight participants.
resultsNew thyroid nodules were detected in 660 participants. Being overweight was positively associated with thyroid nodules. The adjusted odds ratio (95% CI) of thyroid nodules for overweight participants compared with other participants was 1.27 (1.04-1.57). Additionally, the multivariable adjusted odds ratios for overweight males and females were 1.21 and 1.32, respectively, and those for different age groups (0-9, 10-14, and 15-19 years) ranged from 1.17 to 1.75.
conclusionBeing overweight was associated with thyroid nodules in children and adolescents, mostly adolescent females, regardless of their proximity to the nuclear power plant.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.