Evidence map›Paper›PMID 38477429›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Nanowire Array Breath Acetone Sensor for Diabetes Monitoring.

Shiyu Wei, Zhe Li, Krishnan Murugappan, Ziyuan Li, Mykhaylo Lysevych, Kaushal Vora, Hark Hoe Tan, Chennupati Jagadish, Buddini I Karawdeniya, Christopher J Nolan and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Bioengineering Platelets Presenting PD-L1, Galectin-9 and BTLA to Ameliorate Type 1 Diabetes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. Review
  6. Nanowire Array Breath Acetone Sensor for Diabetes Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Shiyu WeiAustralian Research Council Centre of Excellence for Transformative Meta-Optical Systems, Department of Electronic Materials Engineering, Research School of Physics, The Australian National University, Canberra, ACT, 2600, Australia.
Zhe LiAustralian Research Council Centre of Excellence for Transformative Meta-Optical Systems, Department of Electronic Materials Engineering, Research School of Physics, The Australian National University, Canberra, ACT, 2600, Australia.
Krishnan MurugappanCommonwealth Scientific and Industrial Research Organisation (CSIRO), Mineral Resources, Private Bag 10, Clayton South, VIC, 3169, Australia.
Ziyuan LiAustralian Research Council Centre of Excellence for Transformative Meta-Optical Systems, Department of Electronic Materials Engineering, Research School of Physics, The Australian National University, Canberra, ACT, 2600, Australia.
Mykhaylo LysevychAustralian National Fabrication Facility, The Australian National University, Canberra, ACT, 2600, Australia.
Kaushal VoraAustralian National Fabrication Facility, The Australian National University, Canberra, ACT, 2600, Australia.
Hark Hoe TanAustralian Research Council Centre of Excellence for Transformative Meta-Optical Systems, Department of Electronic Materials Engineering, Research School of Physics, The Australian National University, Canberra, ACT, 2600, Australia.
Chennupati JagadishAustralian Research Council Centre of Excellence for Transformative Meta-Optical Systems, Department of Electronic Materials Engineering, Research School of Physics, The Australian National University, Canberra, ACT, 2600, Australia.
Buddini I KarawdeniyaAustralian Research Council Centre of Excellence for Transformative Meta-Optical Systems, Department of Electronic Materials Engineering, Research School of Physics, The Australian National University, Canberra, ACT, 2600, Australia.
Christopher J NolanSchool of Medicine and Psychology, College of Health and Medicine, The Australian National University, Canberra, ACT, 2600, Australia.
Antonio TricoliNanotechnology Research Laboratory, Research School of Chemistry, College of Science, The Australian National University, Canberra, ACT, 2600, Australia.
Lan FuAustralian Research Council Centre of Excellence for Transformative Meta-Optical Systems, Department of Electronic Materials Engineering, Research School of Physics, The Australian National University, Canberra, ACT, 2600, Australia.ORCID 0000-0002-9070-8373
Australian National University · AU

Funding

Australian National University a strategic initiativeAustralian National University Our Health in Our Hands (OHIOH)Australian Research Council Discoverygrant(DP190101864)Australian Research Council FutureFellowshipgrant(FT200100939)China Scholarship CouncilNational Intelligence and Security Discovery Research NS210100083
6 · The paper itself

Abstract

Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes characterized by the accumulation of ketone bodies in the blood. Breath acetone, a ketone, directly correlates with blood ketones. Therefore, monitoring breath acetone can significantly enhance the safety and efficacy of diabetes care. In this work, the design and fabrication of an InP/Pt/chitosan nanowire array-based chemiresistive acetone sensor is reported. By incorporation of chitosan as a surface-functional layer and a Pt Schottky contact for efficient charge transfer processes and photovoltaic effect, self-powered, highly selective acetone sensing is achieved. The sensor has exhibited an ultra-wide acetone detection range from sub-ppb to >100 000 ppm level at room temperature, covering those in the exhaled breath from healthy individuals (300-800 ppb) to people at high risk of DKA (>75 ppm). The nanowire sensor has also been successfully integrated into a handheld breath testing prototype, the Ketowhistle, which can successfully detect different ranges of acetone concentrations in simulated breath samples. The Ketowhistle demonstrates the immediate potential for non-invasive ketone monitoring for people living with diabetes, in particular for DKA prevention.

Indexed as

AcetoneBreath TestsNanowiresBiosensing TechniquesChitosanDiabetes MellitusDiabetic KetoacidosisEquipment DesignHumansAcetoneChitosanacetone sensorbreath test prototypechitosanDiabetic ketoacidosisInP nanowires

Identifiers

PMID38477429
PMCPMC11109654
OpenAlexW4392741229

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.