Evidence map›Paper›PMID 38477213›Full record

ArticleDrug testing and analysis2024

Analysing and quantifying chronic stress-associated endogenous steroids in hair samples.

Katharina Elisabeth Grafinger, Wassilis Kassis, Céline A Favre, Dilan Aksoy, Stefan Gaugler

Open access · hybridAbstract readValidation Study
In one paragraph

Article in Drug testing and analysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Interpol review of forensic drug chemistry, 2022-2025.Forensic science international. Synergy · 2026
    Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Katharina Elisabeth GrafingerInstitute of Chemistry and Bioanalytics, University of Applied Sciences and Arts Northwestern Switzerland, Muttenz, Switzerland.ORCID https://orcid.org/0000-0002-3647-7455
Wassilis KassisInstitute of Research and Development, School of Education, University of Applied Sciences and Arts Northwestern Switzerland, Windisch, Switzerland.ORCID https://orcid.org/0000-0002-7235-2182
Céline A FavreInstitute of Research and Development, School of Education, University of Applied Sciences and Arts Northwestern Switzerland, Windisch, Switzerland.ORCID https://orcid.org/0000-0003-1675-4280
Dilan AksoyInstitute of Research and Development, School of Education, University of Applied Sciences and Arts Northwestern Switzerland, Windisch, Switzerland.ORCID https://orcid.org/0000-0001-6484-7807
Stefan GauglerInstitute of Chemistry and Bioanalytics, University of Applied Sciences and Arts Northwestern Switzerland, Muttenz, Switzerland.ORCID https://orcid.org/0000-0001-9059-0291
FHNW University of Applied Sciences and Arts · CH

Funding

Swiss National Science Foundation 100019_185481University of Applied Sciences and Arts Northwestern Switzerland
6 · The paper itself

Abstract

In previous studies, various steroids have been associated with stress and have therefore been quantified to investigate stress-related questions. Since the main stress-related steroid cortisol follows a circadian rhythm, often hair is analysed to quantify this steroid. Further, hair analysis gives the unique possibility of long-time monitoring by analysing a certain segment of hair, since hair grows on average 1 cm per month. Hair is a difficult matrix due to the complex sample preparation with many steps including washing and grinding, followed by various extraction steps. Additionally, steroids are endogenous and are therefore present in the hair matrix. Hence, no analyte free matrix is available, which is needed for the quantification via external calibrators. To overcome this problem, the so-called surrogate methods can be used, for which a

Indexed as

HairSteroidsAdolescentFemaleGas Chromatography-Mass SpectrometryHumansHydrocortisoneLimit of DetectionStress, PsychologicalHydrocortisoneSteroidscortisolhair analysisLC–MS/MSsteroidsstress

Identifiers

PMID38477213
PMCPMC11635064
OpenAlexW4392741582

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.