ArticleJournal of athletic training2025
Biomechanical Threshold Values for Identifying Clinically Significant Knee-Related Symptoms 6 Months After Anterior Cruciate Ligament Reconstruction.
Article in Journal of athletic training, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed, 10 citations in OpenAlex.
- Increasing dynamic limb-level loading via real-time biofeedback decreases cumulative loading impulse during gait post-anterior cruciate ligament reconstruction.Clinical biomechanics (Bristol, Avon) · 2026Article
- Preventing osteoarthritis after anterior cruciate ligament injury: The case for targeting pre-osteoarthritis illness.Osteoarthritis and cartilage · 2026Article
- Associations between habitual walking speed and in vivo tibial cartilage strain in individuals with anterior cruciate ligament reconstruction.Osteoarthritis imaging · 2026Article
- Elastic Shape Analysis of Movement Data.Journal of the American Statistical Association · 2025Article
- Influence of the Medial and Lateral Posterior Tibial Slope on Anterior Tibial Translation During Gait in Anterior Cruciate Ligament-Deficient Knees.Orthopaedic journal of sports medicine · 2025Article
- Tibiofemoral Joint Contact Force Profiles of Pediatric Patients After Anterior Cruciate Ligament Reconstruction.The American journal of sports medicine · 2025Article
- MRI-derived articular cartilage strains predict patient-reported outcomes six months post anterior cruciate ligament reconstruction.Scientific reports · 2025Article
- Osteoarthritis.Nature reviews. Disease primers · 2025Review
- Bilateral waveform analysis of gait biomechanics presurgery to 12 months following ACL reconstruction compared to controls.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
contextSlower habitual walking speed and aberrant gait biomechanics are linked to clinically significant knee-related symptoms and articular cartilage composition changes linked to posttraumatic osteoarthritis after anterior cruciate ligament reconstruction (ACLR).
objectivesTo (1) determine whether specific gait biomechanical variables can accurately identify individuals with clinically significant knee-related symptoms post-ACLR and (2) determine the corresponding threshold values, sensitivity, specificity, and odds ratios for each biomechanical variable.
designCross-sectional study.
settingLaboratory. PATIENTS OR OTHER
participantsA total of 71 individuals (38 female, 33 male; age = 21 ± 4 years, height = 1.76 ± 0.11 m, mass = 75.38 ± 13.79 kg, time after primary unilateral ACLR = 6.2 ± 0.4 months). MAIN OUTCOME MEASURE(S): Three-dimensional motion capture of 5 overground walking trials was used to calculate discrete gait biomechanical variables of interest during stance phase (first and second peak vertical ground reaction force [vGRF], midstance minimum vGRF, peak internal knee-abduction and -extension moments, and peak knee-flexion angle), along with habitual walking speed. Previously established Knee Injury and Osteoarthritis Outcome Score cutoff scores were used to define patients with (ie, symptomatic; n = 51) and those without (ie, asymptomatic; n = 20) clinically significant knee-related symptoms. Separate receiver operating characteristic curves and respective areas under the curve (AUCs) were used to evaluate the capability of each biomechanical variable of interest to identify individuals with clinically significant knee-related symptoms.
resultsHabitual walking speed (AUC = 0.66), vGRF at midstance (AUC = 0.69), and second peak vGRF (AUC = 0.76) demonstrated low to moderate accuracy for identifying individuals with clinically significant knee-related symptoms. Individuals who exhibited habitual walking speeds ≤ 1.27 m/s, midstance minimum vGRF ≥ 0.82 body weights, and second peak vGRF ≤ 1.11 body weights demonstrated 3.13, 6.36, and 9.57 times higher odds of experiencing clinically significant knee-related symptoms, respectively.
conclusionsCritical thresholds for gait variables may be used to identify individuals with increased odds of clinically significant knee-related symptoms and potential targets for future interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.