Evidence map›Paper›PMID 38477060›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Easy but Efficient: Facile Approach to Molecule with Theoretically Justified Donor-Acceptor Structure for Effective Photothermal Conversion and Intravenous Photothermal Therapy.

Yuan-Hui Zhong, Gui-Feng Huang, Sheng-Yi Zhao, Lai-Hon Chung, Hua-Tang Zhang, Jin-Hong Zheng, Yi-Lang Yan, Wen-Xiu Ni, Jun He

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yuan-Hui ZhongSchool of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, Guangdong, 510006, P. R. China.ORCID 0000-0002-4326-4589
Gui-Feng HuangDepartment of Medicinal Chemistry, Shantou University Medical College, Shantou, Guangdong, 515041, P. R. China.
Sheng-Yi ZhaoSchool of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, Guangdong, 510006, P. R. China.
Lai-Hon ChungSchool of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, Guangdong, 510006, P. R. China.ORCID 0000-0002-0482-1362
Hua-Tang ZhangSchool of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, Guangdong, 510006, P. R. China.
Jin-Hong ZhengDepartment of Medicinal Chemistry, Shantou University Medical College, Shantou, Guangdong, 515041, P. R. China.
Yi-Lang YanDepartment of Medicinal Chemistry, Shantou University Medical College, Shantou, Guangdong, 515041, P. R. China.
Wen-Xiu NiDepartment of Medicinal Chemistry, Shantou University Medical College, Shantou, Guangdong, 515041, P. R. China.
Jun HeSchool of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, Guangdong, 510006, P. R. China.ORCID 0000-0001-7062-4001
Guangdong University of Technology · CNShantou University · CN

Funding

Basic and Applied Basic Research Foundation of Guangdong Province 2019B030302009Basic and Applied Basic Research Foundation of Guangdong Province 2023A1515011759National Natural Science Foundation of China 22301045National Natural Science Foundation of China 22371054
6 · The paper itself

Abstract

To accelerate the pace in the field of photothermal therapy (PTT), it is urged to develop easily accessible photothermal agents (PTAs) showing high photothermal conversion efficiency (PCE). As a proof-of-concept, hereby a conventional strategy is presented to prepare donor-acceptor (D-A) structured PTAs through cycloaddition-retroelectrocyclization (CA-RE) reaction, and the resultant PTAs give high PCE upon near-infrared (NIR) irradiation. By joint experimental-theoretical study, these PTAs exhibit prominent D-A structure with strong intramolecular charge transfer (ICT) characteristics and significantly twisting between D and A units which account for the high PCEs. Among them, the DMA-TCNQ exhibits the strongest absorption in NIR range as well as the highest PCE of 91.3% upon irradiation by 760-nm LED lamp (1.2 W cm

Indexed as

Mice, NudePhotothermal TherapyAnimalsCell Line, TumorDisease Models, AnimalHumansInfrared RaysMiceNeoplasmsantitumorCA–RE reactionD–A junctionphotothermal therapytwisted molecules

Identifiers

PMID38477060
PMCPMC11200029
OpenAlexW4392760759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.